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本文引用的文献

1
Efficacy and predictive factors of transarterial chemoembolization combined with lenvatinib plus programmed cell death protein-1 inhibition for unresectable hepatocellular carcinoma.经动脉化疗栓塞联合乐伐替尼加程序性细胞死亡蛋白-1抑制治疗不可切除肝细胞癌的疗效及预测因素
World J Gastrointest Oncol. 2024 Apr 15;16(4):1236-1247. doi: 10.4251/wjgo.v16.i4.1236.
2
Systemic Drugs for Hepatocellular Carcinoma: What Do Recent Clinical Trials Reveal About Sequencing and the Emerging Complexities of Clinical Decisions?用于肝细胞癌的全身性药物:近期临床试验对治疗顺序及临床决策中日益复杂的情况有何揭示?
J Hepatocell Carcinoma. 2024 Feb 19;11:363-372. doi: 10.2147/JHC.S443218. eCollection 2024.
3
Comparison of tumor response and outcomes of patients with hepatocellular carcinoma after multimodal treatment including immune checkpoint inhibitors - a systematic review and meta-analysis.比较包括免疫检查点抑制剂在内的多种治疗方法后肝细胞癌患者的肿瘤反应和结局 - 系统评价和荟萃分析。
HPB (Oxford). 2024 May;26(5):618-629. doi: 10.1016/j.hpb.2024.02.003. Epub 2024 Feb 9.
4
Safety and Survival Outcomes of Liver Resection following Triple Combination Conversion Therapy for Initially Unresectable Hepatocellular Carcinoma.最初不可切除的肝细胞癌三联联合转化治疗后肝切除的安全性和生存结果
Cancers (Basel). 2023 Dec 17;15(24):5878. doi: 10.3390/cancers15245878.
5
Transarterial Chemoembolization Combined with Tyrosine Kinase Inhibitors Plus Immune Checkpoint Inhibitors for Advanced Hepatocellular Carcinoma: A Propensity Score Matching Analysis.经动脉化疗栓塞联合酪氨酸激酶抑制剂加免疫检查点抑制剂治疗晚期肝细胞癌:一项倾向评分匹配分析
J Hepatocell Carcinoma. 2023 Dec 13;10:2265-2276. doi: 10.2147/JHC.S443041. eCollection 2023.
6
Efficacy and safety of hepatic arterial infusion chemotherapy combined with immune checkpoint inhibitors and tyrosine kinase inhibitors in advanced hepatocellular carcinoma: A systematic review and meta‑analysis.肝动脉灌注化疗联合免疫检查点抑制剂和酪氨酸激酶抑制剂治疗晚期肝细胞癌的疗效与安全性:一项系统评价和荟萃分析。
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Triple combination of HAIC-FO plus tyrosine kinase inhibitors and immune checkpoint inhibitors for advanced hepatocellular carcinoma: A systematic review and meta-analysis.HAIC-FO 三联疗法联合酪氨酸激酶抑制剂和免疫检查点抑制剂治疗晚期肝细胞癌:系统评价和荟萃分析。
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Role of Transarterial Chemoembolization in the Era of Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Combination Therapy for Unresectable Hepatocellular Carcinoma: A Retrospective Propensity Score Matched Analysis.经动脉化疗栓塞在不可切除肝细胞癌的酪氨酸激酶抑制剂和免疫检查点抑制剂联合治疗时代的作用:回顾性倾向评分匹配分析。
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Addition of transarterial chemoembolization improves outcome of tyrosine kinase and immune checkpoint inhibitors regime in patients with unresectable hepatocellular carcinoma.经动脉化疗栓塞术的加入可改善不可切除肝细胞癌患者酪氨酸激酶和免疫检查点抑制剂治疗方案的疗效。
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肝细胞癌经动脉治疗的当前研究现状

Current research status of transarterial therapies for hepatocellular carcinoma.

作者信息

Zhou Mao-Ting, Zhang Peng, Mao Qi, Wei Xiao-Qin, Yang Lin, Zhang Xiao-Ming

机构信息

Department of Radiology, Interventional Medical Center, Science and Technology Innovation Center, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.

School of Medical Imaging, North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.

出版信息

World J Gastrointest Oncol. 2024 Sep 15;16(9):3752-3760. doi: 10.4251/wjgo.v16.i9.3752.

DOI:10.4251/wjgo.v16.i9.3752
PMID:39350995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11438772/
Abstract

With continuous advancements in interventional radiology, considerable progress has been made in transarterial therapies for hepatocellular carcinoma (HCC) in recent years, and an increasing number of research papers on transarterial therapies for HCC have been published. In this editorial, we comment on the article by Ma published in the recent issue of the "Efficacy and predictive factors of transarterial chemoembolization combined with lenvatinib plus programmed cell death protein-1 inhibition for unresectable HCC". We focus specifically on the current research status and future directions of transarterial therapies. In the future, more studies are needed to determine the optimal transarterial local treatment for HCC. With the emergence of checkpoint immunotherapy modalities, it is expected that the results of trials of transarterial local therapy combined with systemic therapy will bring new hope to HCC patients.

摘要

随着介入放射学的不断进步,近年来肝细胞癌(HCC)的经动脉治疗取得了显著进展,并且发表了越来越多关于HCC经动脉治疗的研究论文。在这篇社论中,我们对马[作者姓氏]发表在最近一期《经动脉化疗栓塞联合乐伐替尼加程序性细胞死亡蛋白-1抑制治疗不可切除HCC的疗效和预测因素》上的文章进行评论。我们特别关注经动脉治疗的当前研究现状和未来方向。未来,需要更多研究来确定HCC的最佳经动脉局部治疗方法。随着检查点免疫治疗方式的出现,预计经动脉局部治疗联合全身治疗的试验结果将给HCC患者带来新希望。