Wagner A, Jaizzo P A, Lehmann-Horn F
Klinik für Neurologie, Karl-Marx-Universität Leipzig.
Psychiatr Neurol Med Psychol (Leipz). 1990 Sep;42(9):569-75.
The relationship between electrical and mechanical muscle activity was investigated in the case of twenty patients with myotonia congenita. Statistically significant correlations were found to exist between the myotonic discharge spasm and the phases of tension and relaxation in the mechanogram. In vitro examination for 9-anthracene carbonic acid of individual muscle fiber bundles and the examination of a patient with recessive generalised myotonia revealed that the incidence of myotonic discharge spasms is accompanied by development of tension in the muscle. These findings lend support to the assumption that in both forms of myotonia it is the electrical activity that induces delay of contraction, and thus accounts for the pathological muscle behavior in myotonia.
对20例先天性肌强直患者的电肌肉活动与机械肌肉活动之间的关系进行了研究。发现肌强直放电痉挛与肌动图中的张力和松弛阶段之间存在统计学上的显著相关性。对单个肌纤维束进行的9-蒽碳酸体外检查以及对一名隐性全身性肌强直患者的检查表明，肌强直放电痉挛的发生伴随着肌肉张力的发展。这些发现支持了这样一种假设，即在两种形式的肌强直中，都是电活动导致收缩延迟，从而解释了肌强直中病理性的肌肉行为。
