Department of Ecology and Evolutionary Biology, The University of Arizona, Tucson, AZ 85721, USA.
J Biol Dyn. 2007 Jul;1(3):231-48. doi: 10.1080/17513750701201364.
In a previous paper, we discussed the bifurcation structure of SEIR equations subject to seasonality. There, the focus was on parameters that affect transmission: the mean contact rate, β(0), and the magnitude of seasonality, ε(B). Using numerical continuation and brute force simulation, we characterized a global pattern of parametric dependence in terms of subharmonic resonances and period-doublings of the annual cycle. In the present paper, we extend this analysis and consider the effects of varying non-contact-related parameters: periods of latency, infection and immunity, and rates of mortality and reproduction, which, following the usual practice, are assumed to be equal. The emergence of several new forms of dynamical complexity notwithstanding, the pattern previously reported is preserved. More precisely, the principal effect of varying non-contact related parameters is to displace bifurcation curves in the β(0)-ε(B) parameter plane and to expand or contract the regions of resonance and period-doubling they delimit. Implications of this observation with respect to modeling real-world epidemics are considered.
在之前的一篇论文中,我们讨论了具有季节性的 SEIR 方程的分岔结构。当时,我们关注的是影响传播的参数:平均接触率β(0)和季节性幅度ε(B)。通过数值连续和暴力模拟,我们根据亚谐波共振和年度周期的倍周期来描述参数依赖性的全局模式。在本文中,我们扩展了这一分析,并考虑了变化的非接触相关参数的影响:潜伏期、感染和免疫的周期,以及死亡率和繁殖率,根据惯例,这些参数被假设为相等。尽管出现了几种新形式的动态复杂性,但之前报告的模式仍然存在。更准确地说,改变非接触相关参数的主要影响是在β(0)-ε(B)参数平面上移动分岔曲线,并扩展或收缩它们所限定的共振和倍周期区域。考虑了这一观察结果对现实世界传染病模型的意义。