Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland.
J Biol Dyn. 2008 Jul;2(3):259-85. doi: 10.1080/17513750701769857.
We describe and develop a difference equation model for the dynamics of malaria in a mosquito population feeding on, infecting and getting infected from a heterogeneous population of hosts. Using the force of infection from different classes of humans to mosquitoes as parameters, we evaluate a number of entomological parameters, indicating malaria transmission levels, which can be compared to field data. By assigning different types of vector control interventions to different classes of humans and by evaluating the corresponding levels of malaria transmission, we can compare the effectiveness of these interventions. We show a numerical example of the effects of increasing coverage of insecticide-treated bed nets in a human population where the predominant malaria vector is Anopheles gambiae.
我们描述并开发了一个差分方程模型，用于描述在以感染和被感染的异质宿主种群为食的蚊子种群中疟疾的动态。使用不同人类群体向蚊子传播的感染率作为参数，我们评估了一些昆虫学参数，这些参数可以与实地数据进行比较。通过将不同类型的媒介控制干预措施分配给不同类型的人类，并评估相应的疟疾传播水平，我们可以比较这些干预措施的效果。我们展示了一个数值例子，说明在主要疟疾病媒为冈比亚按蚊的人群中，增加经杀虫剂处理的蚊帐覆盖率的影响。
