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170例患者择期Bentall手术后的结果。

Results of one-hundred and seventy patients after elective Bentall operation.

作者信息

Verbakel Karin M J, van Straten Albert H M, Hamad Mohamed A Soliman, Tan Erwin S H, ter Woorst Joost F

机构信息

Department of Cardiothoracic Surgery, Catharina Hospital, Michelangelolaan 2, Postbus 1350, 5602 ZA Eindhoven, The Netherlands.

出版信息

Asian Cardiovasc Thorac Ann. 2012 Aug;20(4):418-25. doi: 10.1177/0218492312439057.

Abstract

The aim of this study was to evaluate the short and long-term operative results of patients who underwent a Bentall procedure in a 12-year period. We retrospectively analyzed the data of 170 patients who underwent an elective Bentall procedure between January 1998 and July 2010. All pre- and perioperative variable were entered into a multivariate regression model to identify significant predictors of early and late mortality. The early mortality rate was 11.2% (19/170 patients). Multivariate logistic regression analysis identified prior cardiac operation and cardiopulmonary bypass time as independent risk factors for early mortality, with odds ratios of 5.75 (95% confidence interval: 1.850-17.874; p=0.003) and 1.011 (95% confidence interval: 1.003-1.019; p=0.008), respectively. The Kaplan-Meier curve shows an overall survival of 78%±4% at 5 years and 66%±10% at 10 years. Cox regression analysis revealed no independent risk factors for late mortality. The Bentall procedure is still the procedure of choice for aortic root replacement. Improvements in perioperative management in recent years has improved the early outcome, and in our experience, the late results of this technique were satisfactory.

摘要

本研究的目的是评估在12年期间接受Bentall手术患者的短期和长期手术结果。我们回顾性分析了1998年1月至2010年7月期间170例行择期Bentall手术患者的数据。将所有术前和围手术期变量纳入多变量回归模型,以确定早期和晚期死亡率的重要预测因素。早期死亡率为11.2%(19/170例患者)。多变量逻辑回归分析确定既往心脏手术和体外循环时间为早期死亡的独立危险因素,比值比分别为5.75(95%置信区间:1.850 - 17.874;p = 0.003)和1.011(95%置信区间:1.003 - 1.019;p = 0.008)。Kaplan-Meier曲线显示5年总生存率为78%±4%,10年为66%±10%。Cox回归分析未发现晚期死亡的独立危险因素。Bentall手术仍然是主动脉根部置换的首选手术。近年来围手术期管理的改善提高了早期结局,根据我们的经验,该技术的晚期结果令人满意。

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