Leeds Institute of Molecular Medicine, University of Leeds, St James's University Hospital, Leeds, UK.
Histopathology. 2013 Jan;62(2):351-8. doi: 10.1111/j.1365-2559.2012.04323.x. Epub 2012 Aug 8.
To create and evaluate a virtual reality (VR) microscope that is as efficient as the conventional microscope, seeking to support the introduction of digital slides into routine practice.
A VR microscope was designed and implemented by combining ultra-high-resolution displays with VR technology, techniques for fast interaction, and high usability. It was evaluated using a mixed factorial experimental design with technology and task as within-participant variables and grade of histopathologist as a between-participant variable. Time to diagnosis was similar for the conventional and VR microscopes. However, there was a significant difference in the mean magnification used between the two technologies, with participants working at a higher level of magnification on the VR microscope.
The results suggest that, with the right technology, efficient use of digital pathology for routine practice is a realistic possibility. Further work is required to explore what magnification is required on the VR microscope for histopathologists to identify diagnostic features, and the effect on this of the digital slide production process.
开发并评估一种虚拟现实（VR）显微镜，使其与传统显微镜一样高效，力求支持数字切片引入常规实践。
通过将超高分辨率显示器与 VR 技术、快速交互技术和高可用性技术相结合，设计并实现了 VR 显微镜。采用混合因子实验设计，以技术和任务作为组内变量，以组织病理学家的级别作为组间变量对其进行评估。诊断用时在传统显微镜和 VR 显微镜之间相似。然而，两种技术之间使用的平均放大倍数存在显著差异，使用 VR 显微镜的参与者的放大倍数更高。
结果表明，通过正确的技术，高效地将数字病理学用于常规实践是切实可行的。需要进一步研究在 VR 显微镜上需要多大的放大倍数才能让组织病理学家识别诊断特征，以及数字切片制作过程对此的影响。
