Randell Rebecca, Ruddle Roy A, Thomas Rhys G, Mello-Thoms Claudia, Treanor Darren
School of Healthcare, University of Leeds, Leeds LS2 9UT, UK.
School of Computing, University of Leeds, Leeds LS2 9JT, UK.
Hum Pathol. 2014 Oct;45(10):2101-6. doi: 10.1016/j.humpath.2014.06.017. Epub 2014 Jul 2.
Digital pathology promises a number of benefits in efficiency in surgical pathology, yet the longer time required to review a virtual slide than a glass slide currently represents a significant barrier to the routine use of digital pathology. We aimed to create a novel workstation that enables pathologists to view a case as quickly as on the conventional microscope. The Leeds Virtual Microscope (LVM) was evaluated using a mixed factorial experimental design. Twelve consultant pathologists took part, each viewing one long cancer case (12-25 slides) on the LVM and one on a conventional microscope. Total time taken and diagnostic confidence were similar for the microscope and LVM, as was the mean slide viewing time. On the LVM, participants spent a significantly greater proportion of the total task time viewing slides and revisited slides more often. The unique design of the LVM, enabling real-time rendering of virtual slides while providing users with a quick and intuitive way to navigate within and between slides, makes use of digital pathology in routine practice a realistic possibility. With further practice with the system, diagnostic efficiency on the LVM is likely to increase yet more.
数字病理学有望在手术病理学的效率方面带来诸多益处，然而目前查看虚拟切片所需的时间比玻璃切片更长，这是数字病理学常规应用的一个重大障碍。我们旨在创建一种新型工作站，使病理学家能够像在传统显微镜上一样快速查看病例。使用混合因子实验设计对利兹虚拟显微镜（LVM）进行了评估。12名顾问病理学家参与其中，每人在LVM上查看一个长癌症病例（12 - 25张切片），并在传统显微镜上查看一个相同病例。显微镜和LVM的总用时和诊断信心相似，平均切片查看时间也是如此。在LVM上，参与者在查看切片上花费的总任务时间比例显著更高，并且更频繁地重新查看切片。LVM的独特设计能够实时渲染虚拟切片，同时为用户提供在切片内部和之间快速且直观的导航方式，使得在常规实践中使用数字病理学成为一种现实的可能性。随着对该系统的进一步实践，在LVM上的诊断效率可能会进一步提高。
