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[食管癌经胸段食管切除术后肺部感染率的岭回归分析]

[Ridge regression analysis of pulmonary infection rate after transthoracic esophagectomy for esophageal cancer].

作者信息

Wang Li-jun, Gu Lian-bing, Jiang Da-ming, Gao Rong, Xu Ze-ping, Wan Mei-fang, Lu Zhen

机构信息

Department of Anesthesiology, Jiangsu Cancer Hospital, Nanjing 210009, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2012 May 22;92(19):1310-3.

PMID:22883116
Abstract

OBJECTIVE

To identify the influencing factors of pulmonary infections after transthoracic esophagectomy for esophageal cancer.

METHODS

A retrospective review of 349 patients undergoing transthoracic esophagectomy at our hospital for esophageal cancer was performed between January and December 2009. The postoperative pneumonia rate was examined and 26 perioperative factors possibly affecting the postoperative respiratory complications were collected. Ridge regression modeling was performed to determine if a significant association existed between perioperative factors and postoperative pneumonia.

RESULTS

The postoperative pneumonia rate of all patients was 27.8%. Eight perioperative factors were found to have affected significantly the postoperative respiratory complications. The influencing factors included (according to contribution): patient control epidural analgesia (PCEA), diabetes, general anesthesia plus epidural analgesia, other postoperative complications, one lung ventilation (OLV), transfusion volume of red blood cells (RBC), body mass index (BMI) and age.

CONCLUSION

The major influencing factors of pulmonary infection after transthoracic esophagectomy for esophageal cancer are PCEA, diabetes, general anesthesia plus epidural analgesia, other postoperative complications, OLV, transfusion volume of RBC, BMI and age.

摘要

目的

确定食管癌经胸段食管切除术后肺部感染的影响因素。

方法

对2009年1月至12月在我院接受食管癌经胸段食管切除术的349例患者进行回顾性研究。检查术后肺炎发生率,并收集26项可能影响术后呼吸并发症的围手术期因素。采用岭回归模型确定围手术期因素与术后肺炎之间是否存在显著关联。

结果

所有患者的术后肺炎发生率为27.8%。发现八项围手术期因素对术后呼吸并发症有显著影响。影响因素包括(按影响程度):患者自控硬膜外镇痛(PCEA)、糖尿病、全身麻醉加硬膜外镇痛、其他术后并发症、单肺通气(OLV)、红细胞输注量(RBC)、体重指数(BMI)和年龄。

结论

食管癌经胸段食管切除术后肺部感染的主要影响因素为PCEA、糖尿病、全身麻醉加硬膜外镇痛、其他术后并发症、OLV、RBC输注量、BMI和年龄。

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