Liu Guangyuan, Peng Lin, Liu Bin, Wang Kangning, Han Yongtao
Ward 1, Department of Thoracic Surgery, Sichuan Cancer Hospital and Institute, Chengdu, Sichuan 610041, P.R. China.
Clinical Research Standardized Treatment Ward, Department of Medical Oncology, Sichuan Cancer Hospital and Institute, Chengdu, Sichuan 610041, P.R. China.
Oncol Lett. 2019 Mar;17(3):3283-3288. doi: 10.3892/ol.2019.9987. Epub 2019 Jan 29.
Clinical manifestations of patients with pulmonary infection after minimally invasive esophagectomy were analyzed. A total of 500 patients undergoing minimally invasive esophagectomy in Sichuan Cancer Hospital and Institute from January 2015 to December 2016 were consecutively selected, among which 124 patients with pulmonary infection after surgery were taken as the infection group, and the remaining 376 patients were taken as the control group. The clinical data of all patients were collected. The pulmonary infection rate after minimally invasive esophagectomy was calculated, and clinical factors with difference were analyzed using the multivariate logistic regression analysis. There were significant differences in age, long-term smoking history, presence or absence of concurrent basic diseases and vital capacity (P<0.01). The application time of antibiotics and antacids and hospitalization duration in the infection group were obviously longer than those in the control group (P<0.01). Age, long-term smoking history, vital capacity, application time of antibiotics and antacids, hospitalization duration and concurrent diabetes mellitus/coronary heart disease/diseases of respiratory system increase the risk of postoperative pulmonary infection in patients with esophageal cancer, and age, long-term smoking history, diabetes mellitus, diseases of respiratory system and hospitalization duration are independent risk factors for pulmonary infection in patients after minimally invasive esophagectomy.
分析了微创食管癌切除术后肺部感染患者的临床表现。连续选取2015年1月至2016年12月在四川省肿瘤医院及研究所接受微创食管癌切除术的500例患者，其中术后发生肺部感染的124例患者作为感染组，其余376例患者作为对照组。收集所有患者的临床资料。计算微创食管癌切除术后的肺部感染率，并采用多因素logistic回归分析对存在差异的临床因素进行分析。年龄、长期吸烟史、是否合并基础疾病及肺活量方面存在显著差异（P<0.01）。感染组抗生素和抗酸剂的使用时间及住院时间明显长于对照组（P<0.01）。年龄、长期吸烟史、肺活量、抗生素和抗酸剂的使用时间、住院时间以及合并糖尿病/冠心病/呼吸系统疾病会增加食管癌患者术后肺部感染的风险，且年龄、长期吸烟史、糖尿病、呼吸系统疾病及住院时间是微创食管癌切除术后患者肺部感染的独立危险因素。
