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左心室功能对二尖瓣修复后收缩期前向运动发展的影响。

Influence of left ventricular function on development of systolic anterior motion after mitral valve repair.

机构信息

Department of Cardiovascular Surgery, Teikyo University Hospital, Tokyo, Japan.

出版信息

J Thorac Cardiovasc Surg. 2013 Aug;146(2):291-5.e1. doi: 10.1016/j.jtcvs.2012.07.015. Epub 2012 Aug 9.

Abstract

OBJECTIVE

A hyperkinetic heart has been suggested as a risk factor for systolic anterior motion (SAM) after mitral valve repair, but the influence of preoperative left ventricular (LV) function on the development of SAM has not been elucidated.

METHODS

Transthoracic echocardiographic data were retrospectively reviewed in 441 patients who underwent mitral valve repair for degenerative mitral regurgitation. Comparisons were made between patients with and without SAM (SAM cases vs noncases).

RESULTS

The incidence of SAM was 6.1% (27/441). There were no differences in preoperative characteristics and operative procedures between the 2 groups except the prevalence of Barlow disease. The SAM cases exhibited a higher preoperative ejection fraction (EF) (SAM cases, 70.0% ± 7.1%; noncases, 65.1% ± 6.9%; P < .01) and smaller preoperative systolic LV end-systolic dimension (LVDs) (32.0 ± 5.4 mm vs 35.4 ± 5.7 mm; P = .02) than the noncases. The incidence of SAM was significantly associated with greater preoperative EF (P < .01 for trend) and reduced LVDs (P < .01 for trend). SAM did not occur in patients with an impaired (EF < 60%) or enlarged (LVDs > 45 mm) LV. The incidence of SAM was highest among patients with a small hyperkinetic heart.

CONCLUSIONS

The study indicates that the development of SAM after mitral valve repair is associated with preoperative LV function. A small hyperkinetic heart is considered a risk factor for SAM and should be treated with caution.

摘要

目的

有人认为心动过速的心脏是二尖瓣修复术后收缩期前向运动(SAM)的一个危险因素,但术前左心室(LV)功能对 SAM 发展的影响尚未阐明。

方法

回顾性分析 441 例行二尖瓣修复术治疗退行性二尖瓣反流的患者的经胸超声心动图数据。比较有和无 SAM(SAM 病例与非病例)患者之间的差异。

结果

SAM 的发生率为 6.1%(27/441)。两组患者在术前特征和手术操作方面无差异,除了 Barlow 病的患病率。SAM 病例的术前射血分数(EF)较高(SAM 病例,70.0%±7.1%;非病例,65.1%±6.9%;P<.01),术前收缩期 LV 末期内径(LVDs)较小(32.0±5.4 mm 比 35.4±5.7 mm;P=.02)。SAM 的发生率与术前 EF 较大(趋势 P<.01)和 LVDs 降低(趋势 P<.01)显著相关。SAM 不会发生在 EF 降低(EF<60%)或 LVDs 增大(LVDs>45 mm)的 LV 受损患者中。SAM 的发生率在存在小的心动过速心脏的患者中最高。

结论

研究表明,二尖瓣修复术后 SAM 的发生与术前 LV 功能有关。小的心动过速心脏被认为是 SAM 的危险因素,应谨慎处理。

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