• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

白喉棒状杆菌中间亚种 NCTC 5011 基因组草图

Draft genome sequence of Corynebacterium diphtheriae biovar intermedius NCTC 5011.

机构信息

Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, United Kingdom.

出版信息

J Bacteriol. 2012 Sep;194(17):4738. doi: 10.1128/JB.00939-12.

DOI:10.1128/JB.00939-12
PMID:22887653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3415510/
Abstract

We report an annotated draft genome of the human pathogen Corynebacterium diphtheriae bv. intermedius NCTC 5011. This strain is the first C. diphtheriae bv. intermedius strain to be sequenced, and our results provide a useful comparison to the other primary disease-causing biovars, C. diphtheriae bv. gravis and C. diphtheriae bv. mitis. The sequence has been deposited at DDBJ/EMBL/GenBank with the accession number AJVH01000000.

摘要

我们报道了人类病原体中间型白喉棒状杆菌 NCTC 5011 的注释草案基因组。该菌株是第一个被测序的中间型白喉棒状杆菌菌株，我们的结果与其他主要致病生物型，即重型白喉棒状杆菌和中间型白喉棒状杆菌，进行了有益的比较。该序列已在 DDBJ/EMBL/GenBank 中以 AJVH01000000 的 accession number 进行了提交。

相似文献

1
Draft genome sequence of Corynebacterium diphtheriae biovar intermedius NCTC 5011.白喉棒状杆菌中间亚种 NCTC 5011 基因组草图
J Bacteriol. 2012 Sep;194(17):4738. doi: 10.1128/JB.00939-12.
2
The draft genome sequence of Corynebacterium diphtheriae bv. mitis NCTC 3529 reveals significant diversity between the primary disease-causing biovars.白喉棒状杆菌温和亚种 NCTC 3529 的基因组草案序列揭示了主要致病生物型之间的显著多样性。
J Bacteriol. 2012 Jun;194(12):3269. doi: 10.1128/JB.00503-12.
3
Taxonomic status of Corynebacterium diphtheriae biovar Belfanti and proposal of Corynebacterium belfantii sp. nov.白喉棒状杆菌贝尔凡蒂生物变种的分类地位及新种贝尔凡蒂棒状杆菌的提议
Int J Syst Evol Microbiol. 2018 Dec;68(12):3826-3831. doi: 10.1099/ijsem.0.003069. Epub 2018 Oct 24.
4
[Genotypic differences between Corynebacterium diphtheriae biovar gravis and mitis strains].[白喉棒状杆菌重生物变种与轻型菌株之间的基因型差异]
Zh Mikrobiol Epidemiol Immunobiol. 2013 May-Jun(3):24-31.
5
Population genomics and antimicrobial resistance in Corynebacterium diphtheriae.人瘤病毒与口咽癌
Genome Med. 2020 Nov 27;12(1):107. doi: 10.1186/s13073-020-00805-7.
6
Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia.对白喉棒状杆菌的泛基因组研究提供了对经典白喉、心内膜炎和肺炎病例中致病性分离株基因组多样性的深入了解。
J Bacteriol. 2012 Jun;194(12):3199-215. doi: 10.1128/JB.00183-12. Epub 2012 Apr 13.
7
[DNA homology study of Corynebacterium diphtheriae v. gravis groups I, II and III, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (ovis)].[白喉棒状杆菌重型菌群I、II和III、溃疡棒状杆菌及假结核棒状杆菌（绵羊亚种）的DNA同源性研究]
Zh Mikrobiol Epidemiol Immunobiol. 1984 Mar(3):48-55.
8
Transcriptome sequencing of the human pathogen Corynebacterium diphtheriae NCTC 13129 provides detailed insights into its transcriptional landscape and into DtxR-mediated transcriptional regulation.人类病原体白喉棒状杆菌 NCTC 13129 的转录组测序为其转录图谱和 DtxR 介导的转录调控提供了详细的见解。
BMC Genomics. 2018 Jan 25;19(1):82. doi: 10.1186/s12864-018-4481-8.
9
Comparative genomic and phylogenetic analysis of a toxigenic clinical isolate of Corynebacterium diphtheriae strain B-D-16-78 from Malaysia.马来西亚一株产毒白喉棒状杆菌临床分离株 B-D-16-78 的比较基因组学和系统发育分析。
Infect Genet Evol. 2017 Oct;54:263-270. doi: 10.1016/j.meegid.2017.07.015. Epub 2017 Jul 12.
10
A lack of genetic basis for biovar differentiation in clinically important Corynebacterium diphtheriae from whole genome sequencing.通过全基因组测序发现，临床重要的白喉棒状杆菌生物变种分化缺乏遗传基础。
Infect Genet Evol. 2014 Jan;21:54-7. doi: 10.1016/j.meegid.2013.10.019. Epub 2013 Nov 5.

引用本文的文献

1
Whole Genome Sequencing for Surveillance of Diphtheria in Low Incidence Settings.低发病率地区白喉监测的全基因组测序
Front Public Health. 2019 Aug 21;7:235. doi: 10.3389/fpubh.2019.00235. eCollection 2019.
2
Analysis of Corynebacterium diphtheriae macrophage interaction: Dispensability of corynomycolic acids for inhibition of phagolysosome maturation and identification of a new gene involved in synthesis of the corynomycolic acid layer.白喉棒状杆菌与巨噬细胞相互作用的分析：分枝菌酸对抑制吞噬溶酶体成熟的非必需性以及参与分枝菌酸层合成的一个新基因的鉴定
PLoS One. 2017 Jul 7;12(7):e0180105. doi: 10.1371/journal.pone.0180105. eCollection 2017.
3
Next-generation systematics: An innovative approach to resolve the structure of complex prokaryotic taxa.下一代系统学：解决复杂原核生物分类单元结构的创新方法。
Sci Rep. 2016 Dec 7;6:38392. doi: 10.1038/srep38392.
4
Adherence and invasive properties of Corynebacterium diphtheriae strains correlates with the predicted membrane-associated and secreted proteome.白喉棒状杆菌菌株的黏附性和侵袭性与预测的膜相关和分泌蛋白质组相关。
BMC Genomics. 2015 Oct 9;16:765. doi: 10.1186/s12864-015-1980-8.
5
Pilus gene pool variation and the virulence of Corynebacterium diphtheriae clinical isolates during infection of a nematode.菌毛基因库变异与白喉棒状杆菌临床分离株在感染线虫时的毒力。
J Bacteriol. 2013 Aug;195(16):3774-83. doi: 10.1128/JB.00500-13. Epub 2013 Jun 14.
6
Cell envelope of corynebacteria: structure and influence on pathogenicity.棒状杆菌的细胞包膜：结构及其对致病性的影响
ISRN Microbiol. 2013 Jan 21;2013:935736. doi: 10.1155/2013/935736. Print 2013.

本文引用的文献

1
The draft genome sequence of Corynebacterium diphtheriae bv. mitis NCTC 3529 reveals significant diversity between the primary disease-causing biovars.白喉棒状杆菌温和亚种 NCTC 3529 的基因组草案序列揭示了主要致病生物型之间的显著多样性。
J Bacteriol. 2012 Jun;194(12):3269. doi: 10.1128/JB.00503-12.
2
Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia.对白喉棒状杆菌的泛基因组研究提供了对经典白喉、心内膜炎和肺炎病例中致病性分离株基因组多样性的深入了解。
J Bacteriol. 2012 Jun;194(12):3199-215. doi: 10.1128/JB.00183-12. Epub 2012 Apr 13.
3
mGenomeSubtractor: a web-based tool for parallel in silico subtractive hybridization analysis of multiple bacterial genomes.mGenomeSubtractor：一个基于网络的工具，用于对多个细菌基因组进行并行的计算机模拟消减杂交分析。
Nucleic Acids Res. 2010 Jul;38(Web Server issue):W194-200. doi: 10.1093/nar/gkq326. Epub 2010 Apr 30.
4
xBASE, a collection of online databases for bacterial comparative genomics.xBASE，一个用于细菌比较基因组学的在线数据库集合。
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D335-7. doi: 10.1093/nar/gkj140.
5
Mauve: multiple alignment of conserved genomic sequence with rearrangements.Mauve：带重排的保守基因组序列多重比对。
Genome Res. 2004 Jul;14(7):1394-403. doi: 10.1101/gr.2289704.
6
The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129.白喉棒状杆菌NCTC13129的全基因组序列及分析
Nucleic Acids Res. 2003 Nov 15;31(22):6516-23. doi: 10.1093/nar/gkg874.
7
Current approaches to the laboratory diagnosis of diphtheria.白喉实验室诊断的当前方法。
J Infect Dis. 2000 Feb;181 Suppl 1:S138-45. doi: 10.1086/315552.
8
Laboratory review of reference strains of Corynebacterium diphtheriae indicates mistyped intermedius strains.对白喉棒状杆菌参考菌株的实验室检查表明存在中间型菌株分型错误的情况。
J Clin Microbiol. 1993 Nov;31(11):3060-2. doi: 10.1128/jcm.31.11.3060-3062.1993.