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变形链球菌 GS-5 全基因组序列,血清型 c 菌株。

Complete genome sequence of Streptococcus mutans GS-5, a serotype c strain.

机构信息

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.

出版信息

J Bacteriol. 2012 Sep;194(17):4787-8. doi: 10.1128/JB.01106-12.

DOI:10.1128/JB.01106-12
PMID:22887682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3415521/
Abstract

Streptococcus mutans, a principal causative agent of dental caries, is considered to be the most cariogenic among all oral streptococci. Of the four S. mutans serotypes (c, e, f, and k), serotype c strains predominate in the oral cavity. Here, we present the complete genome sequence of S. mutans GS-5, a serotype c strain originally isolated from human carious lesions, which is extensively used as a laboratory strain worldwide.

摘要

变形链球菌是龋齿的主要致病菌,被认为是所有口腔链球菌中致龋性最强的细菌。在变形链球菌的 4 个血清型(c、e、f 和 k)中,c 型菌株在口腔中占优势。本研究中,我们介绍了来源于人类龋齿病变的 c 型菌株 GS-5 的全基因组序列,该菌株被广泛用作世界各地的实验室菌株。

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本文引用的文献

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Complete genome sequence of the serotype k Streptococcus mutans strain LJ23.血清型 k 变异链球菌 LJ23 株的全基因组序列。
J Bacteriol. 2012 May;194(10):2754-5. doi: 10.1128/JB.00350-12.
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The IGS Standard Operating Procedure for Automated Prokaryotic Annotation.IGS 原核生物自动注释标准操作规程。
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BAGEL2: mining for bacteriocins in genomic data.BAGEL2:从基因组数据中挖掘细菌素。
Nucleic Acids Res. 2010 Jul;38(Web Server issue):W647-51. doi: 10.1093/nar/gkq365. Epub 2010 May 12.
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An automatic method for identifying surface proteins in bacteria: SLEP.一种自动识别细菌表面蛋白的方法:SLEP。
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Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific content.变形链球菌的比较基因组分析为染色体重排和物种特异性内容提供了见解。
BMC Genomics. 2009 Aug 5;10:358. doi: 10.1186/1471-2164-10-358.
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Prophinder: a computational tool for prophage prediction in prokaryotic genomes.Prophinder:一种用于原核生物基因组中前噬菌体预测的计算工具。
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Ori-Finder: a web-based system for finding oriCs in unannotated bacterial genomes.Ori-Finder:一种用于在未注释细菌基因组中查找oriC的基于网络的系统。
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Dispensable genes and foreign DNA in Streptococcus mutans.变形链球菌中的非必需基因和外源DNA。
Microbiology (Reading). 2006 Jun;152(Pt 6):1777-1788. doi: 10.1099/mic.0.28647-0.