变形链球菌 GS-5 全基因组序列，血清型 c 菌株。
Complete genome sequence of Streptococcus mutans GS-5, a serotype c strain.
机构信息
Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
出版信息
J Bacteriol. 2012 Sep;194(17):4787-8. doi: 10.1128/JB.01106-12.
Abstract
Streptococcus mutans, a principal causative agent of dental caries, is considered to be the most cariogenic among all oral streptococci. Of the four S. mutans serotypes (c, e, f, and k), serotype c strains predominate in the oral cavity. Here, we present the complete genome sequence of S. mutans GS-5, a serotype c strain originally isolated from human carious lesions, which is extensively used as a laboratory strain worldwide.
摘要
变形链球菌是龋齿的主要致病菌，被认为是所有口腔链球菌中致龋性最强的细菌。在变形链球菌的 4 个血清型（c、e、f 和 k）中，c 型菌株在口腔中占优势。本研究中，我们介绍了来源于人类龋齿病变的 c 型菌株 GS-5 的全基因组序列，该菌株被广泛用作世界各地的实验室菌株。
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