Strzyzewski W
Psychiatr Neurol Med Psychol Beih. 1975;20-21:99-104.
40 patients with endogenic depression, who exhibited an inhibited-mel ancholic symptomatology received Dibenzepin (30 patients) and Imipramin (10 patients) as a mood-elucidating and activating anti-depressant. Exact determinations of blood pressure, pulse rate, the orthostatic-reaction, Schellong's test and the cold-pressure test were carried out on these patients. The results were tabulated. They show fundamentally that (1) the thymoleptic circulatory reaction as a sign of the influence of the vegetative functions makes possible in many cases a prognosis of the secondary effects of treatment and (2) a strong acceleration in the rate of pulse, and a rise in the systolic blood pressure at rest as well as the normalization of the orthostatic-test chiefly indicate an improvement or remission of depression.
40例表现为抑制性忧郁症状的内源性抑郁症患者接受了二苯氮䓬(30例患者)和丙咪嗪(10例患者)治疗,作为情绪舒缓和激活的抗抑郁药。对这些患者进行了血压、脉搏率、直立反应、谢隆试验和冷压试验的精确测定。结果制成表格。从根本上表明:(1)作为植物性功能影响标志的抗抑郁药循环反应在许多情况下使得对治疗的继发效应进行预后判断成为可能;(2)脉搏率的强烈加快、静息时收缩压的升高以及直立试验的正常化主要表明抑郁症有所改善或缓解。