Pediatric liver transplantation: Part I. Choosing and caring for the transplant candidate.

Liver transplantation is now an accepted modality of treatment for acute fulminant hepatic failure, end-stage chronic liver disease and certain hepatic-based inborn errors of metabolism in children. This paper reviews the criteria used in selecting appropriate candidates for transplantation based on a knowledge of the natural history of the underlying disease and the individual patient's condition. Important clinical, laboratory, radiologic and histologic data used to make decisions regarding transplantation are reviewed. Nutritional assessment and management are emphasized as part of the comprehensive evaluation and therapeutic plan to prepare a patient for transplantation.