Department of Radiology, Clínica Radiológica Luiz Felippe Mattoso, Rio de Janeiro, Brazil.
Clin Nucl Med. 2012 Sep;37(9):e225-8. doi: 10.1097/RLU.0b013e318251e474.
In neurolymphomatosis, malignant lymphocytes infiltrate the peripheral nervous system in the presence of a known or unknown hematological malignancy. This report describes the findings of diffusion-weighted MRI and F-FDG PET/CT in a 65-year-old man with hoarseness. Results revealed a mass with restricted diffusion on diffusion-weighted imaging in the right visceral vascular space, increased uptake of F-FDG, and other masses at distant peripheral nerves. Restaging PET/CT showed involvement of the right brachial plexus and right sciatic nerve. Biopsy and immunohistochemistry of the right vagus nerve and cervical lymphadenopathy revealed a diffuse large B-cell non-Hodgkin lymphoma.
神经淋巴瘤病是指恶性淋巴细胞在已知或未知血液系统恶性肿瘤的情况下浸润外周神经系统。本报告描述了一位 65 岁男性因声音嘶哑进行弥散加权 MRI 和 F-FDG PET/CT 的结果。结果显示，在右侧内脏血管间隙的弥散加权成像上可见一肿块，呈弥散受限，FDG 摄取增加，以及其他远处周围神经的肿块。PET/CT 分期显示右侧臂丛和坐骨神经受累。右侧迷走神经和颈部淋巴结活检及免疫组化显示弥漫性大 B 细胞非霍奇金淋巴瘤。
