Wright James G, Kocher Mininder S, Sanders James O
The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
J Pediatr Orthop. 2012 Sep;32 Suppl 2:S91-4. doi: 10.1097/BPO.0b013e31825199fa.
Evidence-based medicine carefully assesses the information available in the literature by assessing both the results and the quality of the underlying studies. Studies are prone to both confounding and bias, and practitioners need to have a basic knowledge of how these factors are affected by various study types. This paper addresses the issues facing various study designs with the goal of helping practitioners understand what they can actually learn from different study designs.
循证医学通过评估基础研究的结果和质量,仔细评估文献中可得的信息。研究容易受到混杂因素和偏倚的影响,从业者需要对这些因素如何受到不同研究类型的影响有基本的了解。本文探讨了各种研究设计面临的问题,目的是帮助从业者明白他们实际上能从不同的研究设计中学到什么。