Department of Diagnostic and Interventional Radiology, Clinic of the Goethe University, Haus 23C UG, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
Int J Cardiovasc Imaging. 2013 Feb;29(2):489-96. doi: 10.1007/s10554-012-0109-2. Epub 2012 Aug 14.
Enlargement and dysfunction of the right ventricle (RV) is a sign and outcome predictor of many cardiopulmonary diseases. Due to the complex geometry of the RV exact volumetry is cumbersome and time-consuming. We evaluated the performance of prototype software for fully automated RV segmentation and volumetry from cardiac CT data. In 50 retrospectively ECG-gated coronary CT angiography scans the endsystolic (RVVmin) and enddiastolic (RVVmax) volume of the right ventricle was calculated fully automatically by prototype software. Manual slice segmentation by two independent radiologists served as the reference standard. Measurement periods were compared for both methods. RV volumes calculated with the software were in strong agreement with the results from manual slice segmentation (Bland-Altman r = 0.95-0.98; p < 0.001; Lin's correlation Rho = 0.87-0.96, p < 0.001) for RVVmax and RVVmin with excellent interobserver agreement between both radiologists (r = 0.97; p < 0.001). The measurement period was significantly shorter with the software (153 ± 9 s) than with manual slice segmentation (658 ± 211 s). The prototype software demonstrated very good performance in comparison to the reference standard. It promises robust RV volume results and minimizes postprocessing time.
右心室（RV）的扩大和功能障碍是许多心肺疾病的标志和预后预测因素。由于 RV 的复杂几何形状，精确的容积测量既繁琐又耗时。我们评估了用于从心脏 CT 数据自动分割和测量 RV 的原型软件的性能。在 50 例回顾性 ECG 门控冠状动脉 CT 血管造影扫描中，通过原型软件自动计算右心室的收缩末期（RVVmin）和舒张末期（RVVmax）容积。由两位独立放射科医生手动进行切片分割作为参考标准。比较了两种方法的测量周期。软件计算的 RV 容积与手动切片分割的结果具有很强的一致性（Bland-Altman r = 0.95-0.98；p < 0.001；Lin 的相关性 Rho = 0.87-0.96，p < 0.001），对于 RVVmax 和 RVVmin，两位放射科医生之间的观察者间一致性也非常好（r = 0.97；p < 0.001）。与手动切片分割（658 ± 211 s）相比，使用软件的测量时间明显更短（153 ± 9 s）。与参考标准相比，原型软件的性能非常出色。它承诺提供稳健的 RV 容积结果，并最大限度地减少后处理时间。
