Centre for Health Sciences Research, University of Salford, Manchester, UK.
Skin Res Technol. 2013 Feb;19(1):e479-89. doi: 10.1111/j.1600-0846.2012.00669.x. Epub 2012 Aug 14.
BACKGROUND/PURPOSE: Friction blisters on the foot are a debilitating pathology that have an impact on activities of daily living and can severely impair function. The purpose of this study was to test the hypotheses that digital infrared thermographic imaging will reveal: 1) a correlation between load application to the skin and the creation of blisters, and 2) a correlation between thermographic readings and contact thermometric temperatures.
Apparatus was developed to cause the formation of heel blisters through controlled load application (70 kPa). One foot of each of the 30 healthy volunteers (21 men and 9 women), with an age range of 31 ± 8 years, was subjected to load until a blister formed, after which load application ceased and temperature measurements were taken at set times during the following 5.5 h. Temperature measurements were also taken using a contact thermometer.
The majority of the participants (77%) blistered within 18 min of load application. All the blisters created showed significant increases in local temperature compared to baseline during blister creation (P < 0.001) and 30 min post-blister creation (P < 0.001). There was a strong correlation between contact thermometry and thermographic temperature data (r > 8).
These results suggest that thermographic images may prove useful for the remote assessment of traumatically damaged foot skin.
背景/目的：足部摩擦水疱是一种使人虚弱的病理状况，会影响日常生活活动，并严重影响功能。本研究的目的是验证以下两个假设：1）皮肤受力与水疱形成之间存在相关性；2）热成像读数与接触式测温读数之间存在相关性。
设计了一种装置，通过控制负载应用（70kPa）来引起脚跟水疱的形成。30 名健康志愿者（21 名男性和 9 名女性）的每只脚都接受了负载，直到形成水疱，然后停止负载，在接下来的 5.5 小时内的设定时间进行温度测量。还使用接触式温度计进行温度测量。
大多数参与者（77%）在 18 分钟内加载后就会起水疱。在水疱形成过程中（P<0.001）和水疱形成后 30 分钟（P<0.001），所有形成的水疱与基线相比均显示出局部温度的显著升高。接触式测温与热成像温度数据之间存在很强的相关性（r>8）。
这些结果表明，热成像图像可能有助于远程评估创伤性损伤的足部皮肤。
