Department of Surgery, Microsurgery and Medicine, University of Sassari, Italy.
Acta Odontol Scand. 2013 May-Jul;71(3-4):599-609. doi: 10.3109/00016357.2012.700063. Epub 2012 Aug 15.
This paper focuses on clinical responses after 7 days of oral exposure to two resin-based materials as desensitizing agents compared to a fluoride varnish and on morphological and analytical study as a means to elucidate the mechanism of action.
The elemental composition of Vertise™ Flow (VF), Universal Dentine Sealant (UDS) and Flor-Opal® Varnish (FOV) were investigated by using an X-ray energy dispersive spectrometer (EDX) in conjunction with a scanning electron microscope (SEM). SEM morphology of the material-treated dentine surfaces and pain reduction ability according to the Visual Analogue Scale (VAS) were evaluated in selected hypersensitive teeth. Post treatments and 7 day controls were recorded with SEM and VAS measurements. Clinical data was analysed with the Student's t-test for paired data, with a 5% significance level.
Silicon, ytterbium and alumina were the most present elements in VF, whilst calcium, chloride, silicon and alumina were highest in UDS. Within a 7 day oral environment all the tested materials modified the treated-dentine surfaces showing tubular occlusion of different morphology. Clinically, the efficacy of all materials was similar after a 7-day examination. However, VAS scores were significantly reduced if compared with the baseline (p < 0.05).
Within the limits of this study, data indicate that both resins are effective in sealing tubules and reducing VAS. A resin-related effect on the dentine's morphology was observed, which may influence the long-term response of the resins in the treatment of dental hypersensitivity, which requires further investigation.
本文重点研究了两种树脂基脱敏剂(即 Vertise™ Flow [VF]和 Universal Dentine Sealant [UDS])与氟化物漆相比,在口服暴露 7 天后的临床反应,并通过形态学和分析研究来阐明其作用机制。
使用 X 射线能量色散光谱仪(EDX)结合扫描电子显微镜(SEM)对 Vertise™ Flow(VF)、通用牙本质密封剂(UDS)和 Flor-Opal® Varnish(FOV)的元素组成进行了研究。在选定的敏感牙齿中,评估了材料处理牙本质表面的 SEM 形态和根据视觉模拟量表(VAS)的疼痛缓解能力。对治疗后和 7 天对照的牙本质进行 SEM 和 VAS 测量。采用配对学生 t 检验对临床数据进行分析,显著性水平为 5%。
VF 中最主要的元素为硅、镱和氧化铝,而 UDS 中含量最高的元素为钙、氯、硅和氧化铝。在 7 天的口服环境中,所有测试材料均改变了处理后的牙本质表面,表现出不同形态的管腔闭塞。临床检查 7 天后,所有材料的疗效相似。然而,与基线相比,VAS 评分明显降低(p < 0.05)。
在本研究范围内,数据表明两种树脂均可有效封闭牙本质小管并降低 VAS。观察到树脂对牙本质形态的影响,这可能会影响树脂在治疗牙本质过敏症中的长期效果,这需要进一步研究。