No 1 Hospital Affiliated to Medical College, Zhejiang University, Stomatology, Zhejiang, China .
Oper Dent. 2010 May-Jun;35(3):279-86. doi: 10.2341/09-346-C.
This in vivo study evaluated the desensitizing efficacy of two one-bottle self-etching adhesives, two dentin desensitizers and a placebo (water).
Thirty-one volunteers with 55 hypersensitive teeth were recruited into this clinical investigation. The sensitive teeth were randomly assigned into five groups and treated with one of the following materials: iBond, Heraeus; Xeno V, Dentsply; Gluma desensitizer, Heraeus; Bifluorid 12, Voco; placebo (water). Mechanical and thermal stimuli were used to assess the tooth sensitivity response. Discomfort interval scale (DIS) scores of the sensitive teeth were recorded at three different investigation times (baseline, immediately and one month after treatment). Impressions were taken from the sensitive teeth at all three different investigation times, and replica models were made for the evaluation of the dentin surfaces by scanning electron microscopy. The Friedman test and the Mann Whitney U-test were used to analyze the data.
All dental materials significantly reduced the dentin hypersensitivity immediately (p < 0.05) and one month after treatment (p < 0.05), with the exception of Bifluorid 12 for mechanical tooth sensitivity. The placebo (water) only caused a short-term effect on the thermal dentin hypersensitivity (p < 0.05). Topical application of the dentin adhesives/desensitizers on sensitive dentinal areas resulted in occlusion of the patent tubules.
The one-bottle self-etching adhesives and dentin desensitizers involved in the current clinical investigation could significantly relieve dentin hypersensitivity immediately and over the course of a month after treatment (except for Bifluorid 12 for tooth mechanical sensitivity). The placebo (water) had an immediate effect on thermal dentin hypersensitivity.
本体内研究评估了两种单瓶自酸蚀黏结剂、两种牙本质脱敏剂和一种安慰剂(水)的脱敏效果。
31 名有 55 颗敏感牙的志愿者参与了本临床研究。敏感牙随机分为五组,分别用以下材料处理:iBond,贺利氏古莎;Xeno V,登士柏;Gluma 脱敏剂,贺利氏古莎;Bifluorid 12,Voco;安慰剂(水)。采用机械和热刺激评估牙齿敏感反应。在三个不同的研究时间(基线、即刻和治疗后一个月)记录敏感牙的不适间隔量表(DIS)评分。在所有三个不同的研究时间从敏感牙上取印模,并制作复制模型,通过扫描电子显微镜评估牙本质表面。采用 Friedman 检验和 Mann-Whitney U 检验进行数据分析。
所有牙科材料均能即刻(p < 0.05)和治疗后一个月(p < 0.05)显著降低牙本质敏感性,机械敏感牙除外 Bifluorid 12。安慰剂(水)仅对热牙本质敏感产生短期效果(p < 0.05)。将牙本质黏结剂/脱敏剂涂于敏感牙本质区域,可封闭开放的小管。
本临床研究中涉及的单瓶自酸蚀黏结剂和牙本质脱敏剂可即刻和治疗后一个月显著缓解牙本质敏感(机械敏感牙除外 Bifluorid 12)。安慰剂(水)对热牙本质敏感有即刻效果。