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1000 例翼状胬肉延伸切除联合广泛结膜移植术后复发和并发症。

Recurrence and complications after 1,000 surgeries using pterygium extended removal followed by extended conjunctival transplant.

机构信息

Queensland Eye Institute, Brisbane, Australia.

出版信息

Ophthalmology. 2012 Nov;119(11):2205-10. doi: 10.1016/j.ophtha.2012.06.021. Epub 2012 Aug 11.

Abstract

OBJECTIVE

To document the recurrence rate and complication rate of pterygium extended removal followed by extended conjunctival transplant.

DESIGN

An open, prospective study of consecutive pterygium patients undergoing pterygium extended removal followed by extended conjunctival transplant.

PARTICIPANTS AND CONTROLS

The study included 1000 consecutive patients undergoing pterygium surgery between August 2001 and September 2009.

INTERVENTIONS

All patients underwent pterygium extended removal followed by extended conjunctival transplant by the author with attempted follow-up for 1 year.

MAIN OUTCOME MEASURES

Recurrence and complication rates.

RESULTS

Follow-up of >1 year was obtained in 99% of patients. There was 1 recurrence in the 1000 surgeries (0.1%) with 95% confidence intervals of 0.003%-0.56% (Fischer exact test). Seven patients required further surgery: 3 had graft replacements, and 1 each for recurrence, strabismus, inclusion cyst, and granuloma. One patient lost 4 lines of vision from a corneal ulcer.

CONCLUSIONS

Pterygium extended removal followed by extended conjunctival transplant results in one of the lowest recurrence rates reported in the world's literature and an acceptable complication rate.

摘要

目的

记录翼状胬肉广泛切除联合广泛结膜移植术后的复发率和并发症发生率。

设计

一项对连续翼状胬肉患者进行的开放性、前瞻性研究,这些患者均接受了翼状胬肉广泛切除联合广泛结膜移植术。

参与者和对照

本研究纳入了 2001 年 8 月至 2009 年 9 月间行翼状胬肉手术的 1000 例连续患者。

干预措施

作者对所有患者均实施了翼状胬肉广泛切除联合广泛结膜移植术,并尝试对患者进行为期 1 年的随访。

主要观察指标

复发率和并发症发生率。

结果

99%的患者获得了 >1 年的随访。在这 1000 例手术中,有 1 例(0.1%)复发,95%置信区间为 0.003%-0.56%(Fischer 确切检验)。7 例患者需要进一步手术:3 例进行了移植物置换,1 例因复发、斜视、包涵囊肿和肉芽肿各 1 例。1 例患者因角膜溃疡损失了 4 行视力。

结论

翼状胬肉广泛切除联合广泛结膜移植术后的复发率处于世界文献报道的最低水平之一,且并发症发生率可接受。

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