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“氢荧光素”技术在翼状胬肉手术中切除Tenon囊的安全性和有效性:一项为期1年的随访研究。

Safety and efficacy of "hydro-fluorescein" technique in removing Tenon in pterygium surgery: a 1-year follow-up study.

作者信息

Abdul-Kadir Mohd-Asyraaf, Hilmi Mohd Radzi, Mohd Kamal Khairidzan

机构信息

Department of Ophthalmology, Universiti Malaysia Sarawak, Sarawak, Malaysia.

Department of Ophthalmology, Kulliyyah of Medicine, International Islamic University Malaysia, Pahang, Malaysia.

出版信息

Eye (Lond). 2025 Apr;39(6):1081-1085. doi: 10.1038/s41433-024-03539-7. Epub 2024 Dec 10.

DOI:10.1038/s41433-024-03539-7
PMID:39658711
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11978794/
Abstract

PURPOSE

To assess the effectiveness and safety of the "hydro-fluorescein" adjunct technique for primary pterygium removal.

DESIGN/METHODS: A non-randomized prospective study was conducted for various types of pterygium excision with superior bulbar conjunctival autograft (CAG) and fibrin glue. We introduced fluorescein staining to ensure thorough elimination of the Tenon tissue around the bare sclera area and the CAG. The primary outcome was the recurrence rate, and the secondary outcome was any complication associated with fluorescein staining.

RESULTS

Ninety-three participants with primary pterygium of Grades 1-3 were recruited and all completed follow-up for at least 1 year. No recurrence was identified during the follow-up period and no long-term adverse reactions were reported with the "hydro-fluorescein" method.

CONCLUSION

"Hydro-fluorescein" is effective and a safe adjunct in primary pterygium removal and is effective in various grades of pterygia to minimize recurrence with no adverse reaction within 1 year.

摘要

目的

评估“水荧光素”辅助技术用于原发性翼状胬肉切除的有效性和安全性。

设计/方法:采用非随机前瞻性研究,对各类翼状胬肉切除联合上方球结膜自体移植(CAG)及纤维蛋白胶的情况进行研究。我们引入荧光素染色以确保彻底清除裸露巩膜区域及CAG周围的Tenon组织。主要结局指标为复发率,次要结局指标为与荧光素染色相关的任何并发症。

结果

招募了93例1-3级原发性翼状胬肉患者,所有患者均完成了至少1年的随访。随访期间未发现复发情况,且“水荧光素”方法未报告长期不良反应。

结论

“水荧光素”在原发性翼状胬肉切除中是一种有效且安全的辅助手段,对各级翼状胬肉均有效,可最大程度减少复发,且1年内无不良反应。

相似文献

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Safety and efficacy of "hydro-fluorescein" technique in removing Tenon in pterygium surgery: a 1-year follow-up study.“氢荧光素”技术在翼状胬肉手术中切除Tenon囊的安全性和有效性:一项为期1年的随访研究。
Eye (Lond). 2025 Apr;39(6):1081-1085. doi: 10.1038/s41433-024-03539-7. Epub 2024 Dec 10.
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本文引用的文献

1
Pterygium: an update on pathophysiology, clinical features, and management.翼状胬肉:病理生理学、临床特征及治疗的最新进展
Ther Adv Ophthalmol. 2021 May 31;13:25158414211020152. doi: 10.1177/25158414211020152. eCollection 2021 Jan-Dec.
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Pterygium: new insights.翼状胬肉:新的认识。
Eye (Lond). 2020 Jun;34(6):1047-1050. doi: 10.1038/s41433-020-0786-3. Epub 2020 Feb 6.
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Optical coherence tomography angiography in diabetic retinopathy: a review of current applications.光学相干断层扫描血管造影在糖尿病视网膜病变中的应用:当前应用综述
Eye Vis (Lond). 2019 Nov 18;6:37. doi: 10.1186/s40662-019-0160-3. eCollection 2019.
4
Modified Sutureless and Glue-Free Method Versus Conventional Sutures for Conjunctival Autograft Fixation in Primary Pterygium Surgery: A Randomized Controlled Trial.改良免缝合法与常规缝线在原发性翼状胬肉手术中固定结膜移植物的比较:一项随机对照试验。
Cornea. 2019 Nov;38(11):1351-1357. doi: 10.1097/ICO.0000000000002137.
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Corneo-pterygium total area measurements utilising image analysis method.采用图像分析方法测量角膜-翼状胬肉总面积。
J Optom. 2019 Oct-Dec;12(4):272-277. doi: 10.1016/j.optom.2019.04.001. Epub 2019 May 13.
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Estimates of visual impairment and its causes from the National Eye Survey in Malaysia (NESII).马来西亚国家眼部调查(NESII)对视力障碍及其原因的估计。
PLoS One. 2018 Jun 26;13(6):e0198799. doi: 10.1371/journal.pone.0198799. eCollection 2018.
7
Current approaches and future directions in the management of pterygium.翼状胬肉治疗的当前方法与未来方向
Int J Ophthalmol. 2018 May 18;11(5):709-711. doi: 10.18240/ijo.2018.05.01. eCollection 2018.
8
Fluorescence-Guided Surgery.荧光引导手术
Front Oncol. 2017 Dec 22;7:314. doi: 10.3389/fonc.2017.00314. eCollection 2017.
9
Efficacy and Safety of a Large Conjunctival Autograft for Recurrent Pterygium.大面积结膜自体移植治疗复发性翼状胬肉的疗效与安全性
Korean J Ophthalmol. 2017 Dec;31(6):469-478. doi: 10.3341/kjo.2016.0135.
10
Comparison among adjuvant treatments for primary pterygium: a network meta-analysis.原发性翼状胬肉辅助治疗方法的比较:网络荟萃分析。
Br J Ophthalmol. 2018 Jun;102(6):748-756. doi: 10.1136/bjophthalmol-2017-310288. Epub 2017 Nov 16.