MacGregor E A, Chia H, Vohrah R C, Wilkinson M
City of London Migraine Clinic.
Cephalalgia. 1990 Dec;10(6):305-10. doi: 10.1046/j.1468-2982.1990.1006305.x.
To define the term "menstrual" migraine and to determine the prevalence of "menstrual" migraine in women attending the City of London Migraine Clinic.
Women attending the clinic were asked to keep a record of their migraine attacks and menstrual periods for at least 3 complete menstrual cycles.
Fifty-five women completed the study. "Menstrual" migraine was defined as "migraine attacks which occur regularly on or between days -2 to +3 of the menstrual cycle and at no other time". Using this criterion, 4 (7.2%) of the women in our population had "menstrual" migraine. All 4 women had migraine without aura. A further 19 (34.5%) had an increased number of attacks at the time of menstruation in addition to attacks at other times of the cycle. Eighteen (32.7%) had attacks occurring throughout the cycle but with no increase in number at the time of menstruation. Fourteen (25.5%) had no attacks within the defined period during the 3 cycles studied.
A small percentage of women have attacks only occurring at the time of menstruation, which can be defined as true "menstrual" migraine. This group is most likely to respond to hormonal treatment. The group of 34.5% who have an increased number of attacks at the time of menstruation in addition to attacks at other times of the month could be defined as having "menstrually related" migraine and might well respond to hormonal therapy. The 32.7% who have attacks throughout the menstrual cycle without an increase at menstruation are unlikely to respond to hormonal therapy. The 25.5% who do not have attacks related to menstruation almost certainly will not respond to hormonal therapy.
定义“经期性”偏头痛这一术语，并确定在伦敦市偏头痛诊所就诊的女性中“经期性”偏头痛的患病率。
要求在该诊所就诊的女性记录其偏头痛发作情况和月经周期，至少记录3个完整的月经周期。
55名女性完成了该研究。“经期性”偏头痛被定义为“在月经周期的第-2天至+3天或这几天期间规律发作，且在其他时间不发作的偏头痛”。根据这一标准，我们研究人群中有4名（7.2%）女性患有“经期性”偏头痛。这4名女性均为无先兆偏头痛。另有19名（34.5%）女性除了在月经周期其他时间发作外，在月经期间发作次数增加。18名（32.7%）女性在整个月经周期都有发作，但在月经期间发作次数未增加。14名（25.5%）女性在研究的3个周期内的规定时间段内未发作。
一小部分女性仅在月经期间发作偏头痛，这可被定义为真正的“经期性”偏头痛。这一组最有可能对激素治疗有反应。在月经期间发作次数增加且在每月其他时间也有发作的34.5%这一组可被定义为患有“与月经相关的”偏头痛，很可能对激素治疗有反应。在整个月经周期都有发作且在月经期间发作次数未增加的32.7%这一组不太可能对激素治疗有反应。在月经期间无发作的25.5%这一组几乎肯定不会对激素治疗有反应。
