Mendes Karina Giane, Theodoro Heloísa, Rodrigues Alice Dalpicolli, Olinto Maria Teresa Anselmo
Centro de Ciências Biológicas e da Saúde, Universidade de Caxias do Sul, Brasil.
Cad Saude Publica. 2012 Aug;28(8):1423-37. doi: 10.1590/s0102-311x2012000800002.
Metabolic syndrome is a complex disorder involving a combination of cardiovascular risk factors. Menopausal transition can be a key factor in the increased prevalence of metabolic syndrome. The current study aims to evaluate the prevalence of metabolic syndrome and its components in the menopausal transition, using a systematic review. Three reviewers conducted an article search in PubMed. The articles' quality was evaluated according to Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). Based on the selected studies, prevalence of metabolic syndrome increases in the post-menopausal (as compared to pre-menopausal) period, regardless of the population and study design. The change was more significant for waist circumference and blood pressure, suggesting that these components have the greatest influence on prevalence of metabolic syndrome.
代谢综合征是一种涉及多种心血管危险因素的复杂病症。绝经过渡可能是代谢综合征患病率增加的一个关键因素。本研究旨在通过系统评价来评估绝经过渡期间代谢综合征及其各组分的患病率。三名评审员在PubMed上进行了文献检索。根据《加强流行病学观察性研究报告规范》(STROBE)对文献质量进行了评估。基于所选研究,无论人群和研究设计如何,绝经后(与绝经前相比)代谢综合征的患病率都会增加。腰围和血压的变化更为显著,这表明这些组分对代谢综合征患病率的影响最大。