Department of Orthopaedics, Xiangya Hospital, Central South University, #87 Xiangya Road, Changsha, 410008, Hunan, China.
Knee Surg Sports Traumatol Arthrosc. 2013 Apr;21(4):804-15. doi: 10.1007/s00167-012-2166-4. Epub 2012 Aug 15.
The aim of this meta-analysis was to examine the effect of the intercondylar notch dimensions, intercondylar notch width index (NWI) and intercondylar notch width (NW), separately in anterior cruciate ligament (ACL) injury.
The PubMed and Wanfang database were searched through until 1 November 2011 to identify studies that met pre-stated inclusion criteria. Reference lists of retrieved articles were also reviewed. Two authors independently extracted information on the designs of the studies, the characteristics of the study participants, exposure and outcome assessments and control for potential confounding factors. Either a fixed- or a random-effects model was used to calculate the overall weighted mean difference (WMD).
Sixteen studies (n = 4,291) were included (1,222 subjects in ACL-injured group and 3,069 subjects in the control group). Statistically significant differences were observed in the NWI (WMD, -0.02; 95 % confidence interval, -0.04 to -0.01), and in the NW (WMD, -2.15; 95 % confidence interval, -3.09 to -1.21) among the ACL-injured group when compared to the control group.
The meta-analysis findings concluded that narrow intercondylar notch dimensions were associated with the risk of ACL injury. A lower NWI or NW stenosis predisposes an individual to ACL injury. Further original studies should include more anatomical risk factors that could be associated with the risk of ACL injury.
本荟萃分析的目的是研究髁间切迹的尺寸(包括髁间切迹宽度指数[NWI]和髁间切迹宽度[NW])对前交叉韧带(ACL)损伤的影响。
通过检索PubMed 和万方数据库,查找符合既定纳入标准的研究。还对检索到的文章的参考文献进行了综述。两位作者独立提取研究设计、研究参与者特征、暴露和结局评估以及潜在混杂因素的控制等信息。使用固定效应模型或随机效应模型计算总加权均数差(WMD)。
纳入了 16 项研究(n = 4291)(ACL 损伤组 1222 例,对照组 3069 例)。与对照组相比,ACL 损伤组的 NWI(WMD,-0.02;95%置信区间,-0.04 至-0.01)和 NW(WMD,-2.15;95%置信区间,-3.09 至-1.21)差异有统计学意义。
荟萃分析结果表明,髁间切迹狭窄与 ACL 损伤的风险相关。NWI 或 NW 狭窄使个体易患 ACL 损伤。进一步的原始研究应包括更多与 ACL 损伤风险相关的解剖学危险因素。