Hospital for Sick Children, Toronto, Ont.
Can Fam Physician. 2012 Aug;58(8):836-8.
Many of my patients experience constipation during pregnancy, even after increasing dietary fibre and fluids. Are there any safe treatments I can recommend to them?
Although the recommended first-line therapy for constipation includes increasing fibre, fluids, and exercise, these are sometimes ineffective. Therefore, laxatives such as bulk-forming agents, lubricant laxatives, stool softeners, osmotic laxatives, and stimulant laxatives might be considered. Although few of the various types of laxatives have been assessed for safety in pregnancy, they have minimal systemic absorption. Therefore, they are not expected to be associated with an increased risk of congenital anomalies. However, it is recommended that osmotic and stimulant laxatives be used only in the short term or occasionally to avoid dehydration or electrolyte imbalances in pregnant women.
我的许多患者在怀孕期间都经历过便秘,即使增加了膳食纤维和液体摄入也是如此。我可以向他们推荐哪些安全的治疗方法?
尽管便秘的推荐一线治疗包括增加膳食纤维、液体和运动,但这些方法有时并不有效。因此,可能会考虑使用泻药,如容积性泻药、润滑剂泻药、大便软化剂、渗透性泻药和刺激性泻药。尽管各种类型的泻药中只有少数几种已被评估用于妊娠安全性,但它们的全身吸收很少。因此,预计它们不会增加先天性畸形的风险。然而,建议仅在短期内或偶尔使用渗透性和刺激性泻药,以避免孕妇脱水或电解质失衡。