Mohiuddin A K
Department of Pharmacy, World University of Bangladesh, Bangladesh.
Innov Pharm. 2019 Jul 5;10(3). doi: 10.24926/iip.v10i3.1659. eCollection 2019.
About 80% of the population worldwide use a variety of traditional medicine, including herbal medicines, for the diagnosis, prevention and treatment of illnesses, and for the improvement of general well-being. Total consumer spending on herbal dietary supplements in the United States reached an estimated $8.085 billion in 2017. In addition, the 8.5% increase in total sales from 2016 is the strongest growth for these products in more than 15 years. The main reason to use herbal products in these countries is the assumption of a better tolerability compared to synthetic drugs. Whereas in developing countries herbal medicines are mostly the only available and affordable treatment option. Surveys from industrialized countries reveal as main health areas in which herbal products are used for upper airway diseases including cough and common cold; other leading causes are gastrointestinal, nervous and urinary complaints up to painful conditions such as rheumatic diseases, joint pain and stiffness. Gastrointestinal disorders are the most widespread problems in health care. Many factors may upset the GI tract and its motility (or ability to keep moving), including: eating a diet low in fiber; lack of motion or sedentary lifestyle; frequent traveling or changes in daily routine; having excessive dairy products; anxiety and depression; resisting the urge to have a bowel movement habitually or due to pain of hemorrhoids; misuse of laxatives (stool softeners) that, over time, weaken the bowel muscles; calcium or aluminum antacids, antidepressants, iron pills, narcotics; pregnancy. About 30% to 40% of adults claim to have frequent indigestion, and over 50 million visits are made annually to ambulatory care facilities for symptoms related to the digestive system. Over ten million endoscopies and surgical procedures involving the GI tract are performed each year. Community-based studies from around the world demonstrate that 10% to 46% of all children meet the criteria for RAP. Gastrointestinal disorders such as chronic or acute diarrhea, malabsorption, abdominal pain, and inflammatory bowel diseases can indicate immune deficiency, present in 5% to 50% of patients with primary immunodeficiencies. The gastrointestinal tract is the largest lymphoid organ in the body, so it is not surprising that intestinal diseases are common among immunodeficient patients. Gastroenterologists therefore must be able to diagnose and treat patients with primary immunodeficiency. Further, pathogens do influence the gut function. On the other hand, dietary habits and specific food types can play a significant role in the onset, treatment, and prevention of many GI disorders. Many of these can be prevented or minimized by maintaining a healthy lifestyle, and practicing good bowel habits.
全球约80%的人口使用包括草药在内的各种传统医学进行疾病的诊断、预防和治疗,以及改善总体健康状况。2017年,美国草药膳食补充剂的消费者总支出估计达到80.85亿美元。此外,与2016年相比,总销售额增长了8.5%,这是这些产品15多年来最强劲的增长。在这些国家使用草药产品的主要原因是认为其耐受性优于合成药物。而在发展中国家,草药大多是唯一可用且负担得起的治疗选择。来自工业化国家的调查显示,草药产品用于上呼吸道疾病(包括咳嗽和普通感冒)是主要的健康领域;其他主要原因是胃肠道、神经和泌尿系统疾病,直至诸如风湿性疾病、关节疼痛和僵硬等疼痛性疾病。胃肠道疾病是医疗保健中最普遍的问题。许多因素可能会扰乱胃肠道及其蠕动(或持续蠕动的能力),包括:饮食中纤维含量低;缺乏运动或久坐不动的生活方式;频繁旅行或日常作息改变;食用过多乳制品;焦虑和抑郁;习惯性抑制排便冲动或因痔疮疼痛;长期滥用泻药(大便软化剂)会削弱肠道肌肉;钙或铝抗酸剂、抗抑郁药、铁剂、麻醉剂;怀孕。约30%至40%的成年人声称经常消化不良,每年有超过5000万人次因消化系统相关症状前往门诊护理机构就诊。每年进行超过1000万例涉及胃肠道的内窥镜检查和外科手术。来自世界各地的社区研究表明,所有儿童中有10%至46%符合复发性腹痛的标准。胃肠道疾病,如慢性或急性腹泻、吸收不良、腹痛和炎症性肠病,可能表明存在免疫缺陷,在5%至50%的原发性免疫缺陷患者中存在。胃肠道是人体最大的淋巴器官,因此肠道疾病在免疫缺陷患者中很常见也就不足为奇了。因此,胃肠病学家必须能够诊断和治疗原发性免疫缺陷患者。此外,病原体确实会影响肠道功能。另一方面,饮食习惯和特定食物类型在许多胃肠道疾病的发生、治疗和预防中可能起重要作用。通过保持健康的生活方式和养成良好的排便习惯,许多这些疾病可以得到预防或最小化。