通过聚苯乙烯微量滴定板的新型串联非共价-共价修饰制备糖芯片及其与活细胞的相互作用研究。
Glycoarrays by a new tandem noncovalent-covalent modification of polystyrene microtiter plates and their interrogation with live cells.
机构信息
Otto Diels Institute of Organic Chemistry, Christiana Albertina University of Kiel, Otto-Hahn-Platz 3-4, 24098 Kiel (Germany).
出版信息
Chembiochem. 2012 Sep 3;13(13):1874-9. doi: 10.1002/cbic.201200365. Epub 2012 Aug 14.
PMID:22893609
Abstract
Glycoarrays--easier than ever: Glycoarrays were fabricated on polystyrene microtiter plates with great ease by using a tandem process that combined hydrophobic adsorption and thiourea bridging. They were validated by testing specific bacterial adhesion and its inhibition.
摘要
糖芯片——前所未有地简单：糖芯片通过使用疏水吸附和硫脲桥接相结合的串联工艺，非常容易地在聚苯乙烯微量滴定板上进行制备。通过测试特定的细菌黏附和抑制作用对其进行了验证。
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