Ren Lei, Yin Fang-Fang, Chetty Indrin J, Jaffray David A, Jin Jian-Yue
Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Med Phys. 2012 Aug;39(8):5099-110. doi: 10.1118/1.4736826.
To evaluate the feasibility of a synchronized moving grid (SMOG) system to remove scatter artifacts, improve the contrast-to-noise ratio (CNR), and reduce image lag artifacts in cone-beam CT (CBCT).
The SMOG system proposed here uses a rapidly oscillating, synchronized moving grid attached to the kV source. Multiple partial projections are taken at different grid positions to form a complete projection in each gantry position, before the gantry moves to the next position during a scan. The grid has a low transmission factor, and it is used for both scatter reduction and scatter measurement for postscan scatter correction. Experimental studies using a static grid and an enlarged CATphan phantom were performed to evaluate the potential CNR enhancement for different SMOG exposure numbers (1, 2, and 4). Simulation studies were performed to evaluate the image lag correction for different exposure numbers (2, 3, and 4) and grid interspace widths in SMOG using the data from an anthropomorphic pelvis phantom scan. Imaging dose of SMOG was also estimated by measuring the imaging dose in a CIRS CT dose phantom using a static grid.
SMOG can enhance the CNR by 16% and 13% when increasing exposure number from 1 to 2 and from 2 to 4, respectively. This enhancement was more dramatic for larger phantoms and smaller initial exposure numbers. Simulation results indicated that SMOG could reduce the lag to less than 4.3% for 2-exposure mode and to less than 0.8% for 3-exposure mode when the grid interspace width was 1.4 cm. Increasing the number of exposures in SMOG dramatically reduced the residual lag in the image. Reducing the grid interspace width somewhat reduced the residual lag. Skin line artifacts were removed entirely in SMOG. Point dose measurement showed that imaging dose of SMOG at isocenter was similar as that of a conventional CBCT.
Compared to our previously developed static-grid dual-rotation method, the proposed SMOG technique has the advantages of enhancing the CNR, correcting the image lag, and reducing the delivery time. Once implemented, SMOG has the potential to remove scatter and image lag artifacts, and significantly enhance CNR for CBCT using the same scanning time as conventional CBCT.
评估同步移动滤线栅(SMOG)系统去除散射伪影、提高对比噪声比(CNR)以及减少锥形束CT(CBCT)中图像滞后伪影的可行性。
本文提出的SMOG系统使用一个快速振荡、同步移动的滤线栅,该滤线栅附着于千伏源。在扫描过程中,在机架移动到下一个位置之前,在不同的滤线栅位置采集多个部分投影,以在每个机架位置形成一个完整的投影。该滤线栅具有低透射系数,用于扫描后散射校正的散射减少和散射测量。使用静态滤线栅和放大的CATphan模体进行实验研究,以评估不同SMOG曝光次数(1、2和4)下潜在的CNR增强。使用来自仿真人体骨盆模体扫描的数据进行模拟研究,以评估不同曝光次数(2、3和4)以及SMOG中滤线栅间隙宽度下的图像滞后校正。还通过使用静态滤线栅测量CIRS CT剂量模体中的成像剂量来估计SMOG的成像剂量。
当曝光次数从1增加到2以及从2增加到4时,SMOG分别可将CNR提高16%和13%。对于更大的模体和更小的初始曝光次数,这种增强更为显著。模拟结果表明,当滤线栅间隙宽度为1.4 cm时,对于2次曝光模式,SMOG可将滞后减少到小于4.3%,对于3次曝光模式可减少到小于0.8%。增加SMOG中的曝光次数可显著减少图像中的残留滞后。减小滤线栅间隙宽度可在一定程度上减少残留滞后。SMOG完全消除了皮肤线伪影。点剂量测量表明,SMOG在等中心处的成像剂量与传统CBCT相似。
与我们之前开发的静态滤线栅双旋转方法相比,所提出的SMOG技术具有增强CNR、校正图像滞后和减少扫描时间的优点。一旦实施,SMOG有可能去除散射和图像滞后伪影,并在与传统CBCT相同的扫描时间内显著提高CBCT的CNR。