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基于傅里叶域光学相干层析术的调制反卷积轴向分辨率改善。

Axial resolution improvement by modulated deconvolution in Fourier domain optical coherence tomography.

机构信息

University of Cyprus, KIOS Research Center for Intelligent Systems and Networks, Department of Electrical and Computer Engineering, 1678 Nicosia, Cyprus.

出版信息

J Biomed Opt. 2012 Jul;17(7):071307. doi: 10.1117/1.JBO.17.7.071307.

Abstract

A novel technique for axial resolution improvement in Fourier domain optical coherence tomography (FDOCT) is presented. The technique is based on the deconvolution of modulated optical coherence tomography signals. In FDOCT, the real part of the Fourier transform of the interferogram is modulated by a frequency which depends on the position of the interferogram in k space. A slight numerical k shift results in a different modulation frequency. By adding two shifted signals, beating can appear in the A-scan. When the amount of shifting is appropriately selected, deconvolution of the resulting depth profile, using suitable modulated kernels, yields a narrower resolution width. A resolution improvement by a factor of ∼7 can be achieved without the need for a broader bandwidth light source.

摘要

提出了一种在傅里叶域光学相干断层扫描(FDOCT)中提高轴向分辨率的新方法。该技术基于对调制光学相干断层扫描信号的反卷积。在 FDOCT 中,干涉图的傅里叶变换的实部被一个频率调制,该频率取决于干涉图在 k 空间中的位置。稍微的数值 k 偏移会导致不同的调制频率。通过添加两个偏移的信号,可以在 A 扫描中出现拍频。当选择适当的偏移量时,使用合适的调制核对所得深度轮廓进行反卷积,可以得到更窄的分辨率宽度。在不需要更宽带宽光源的情况下,可以实现约 7 倍的分辨率提高。

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