Concordia University, Optical Bio-Microsystems Laboratory, Department of Mechanical and Industrial Engineering, Montreal, H3G 1M8, Canada.
J Biomed Opt. 2012 Jul;17(7):077001. doi: 10.1117/1.JBO.17.7.077001.
Three-dimensional gold nanostructures fabricated through a novel convective assembly method are treated thermally to obtain a nanoisland morphology. The new structure is proved to be adequate for the detection of bovine growth hormone, by using an immunoassay method based on the localized surface plasmon resonance band of gold. The nanoisland structures are integrated into a microfluidic device and the spectral measurements are carried out by introducing the device directly in the light beam of a ultraviolet-visible spectrophotometer. The principal motivation for this work is the need for a simple and rapid method of detection of hormone levels in milk and milk products.
通过一种新颖的对流组装方法制造的三维金纳米结构经过热处理可获得纳米岛形态。通过基于金的局域表面等离子体共振带的免疫测定方法，证明新结构可用于检测牛生长激素。将纳米岛结构集成到微流控装置中，并通过将装置直接引入紫外-可见分光光度计的光束中来进行光谱测量。这项工作的主要动机是需要一种简单快速的方法来检测牛奶和奶制品中的激素水平。
