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横纹肌溶解症和镰状细胞特征运动员的急性肾衰竭:病例研究。

Rhabdomyolysis and acute renal failure in a sickle cell trait athlete: a case study.

机构信息

Department of Health, Human Performance and Recreation, School of Education, Baylor University, Waco, Texas 76798-7304, USA

出版信息

Clin J Sport Med. 2013 May;23(3):235-7. doi: 10.1097/JSM.0b013e3182625a37.

DOI:10.1097/JSM.0b013e3182625a37
PMID:22894971
Abstract

This case study reports the clinical details and pathologic mechanisms of a nonfatal case of rhabdomyolysis secondary to heat exhaustion and sickle cell trait (SCT) resulting in acute renal failure. A 19-year-old African American male college football player collapsed after running 5 intervals of 300 m during a preseason conditioning test. After 17 days of treatment, the athlete was released from the hospital to a short-term noncritical care facility for further treatment and dialysis. Scientific literature reports that at least 15 college football players with SCT have died as a result of a sickling crisis after intense physical exertion. This case study presents the clinical importance of prompt medical treatment and sustained low-efficiency dialysis in treating rhabdomyolysis and its sequelae after collapse in an SCT athlete.

摘要

本病例研究报告了一例非致命性横纹肌溶解症的临床细节和病理机制,该病例由热衰竭和镰状细胞特征(SCT)引起,导致急性肾衰竭。一名 19 岁的非裔美国男性大学生橄榄球队员在进行赛前体能测试时跑完 5 个 300 米区间后突然晕倒。经过 17 天的治疗,该运动员从医院出院到短期非重症监护病房进行进一步治疗和透析。科学文献报告称,至少有 15 名 SCT 大学生橄榄球队员在剧烈体力活动后出现镰状细胞危象而死亡。本病例研究提出了在 SCT 运动员晕倒后,及时进行医疗治疗和持续低效透析对治疗横纹肌溶解症及其后果的临床重要性。

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Rhabdomyolysis and acute renal failure in a sickle cell trait athlete: a case study.横纹肌溶解症和镰状细胞特征运动员的急性肾衰竭:病例研究。
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引用本文的文献

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Challenging Return to Play Decisions: Heat Stroke, Exertional Rhabdomyolysis, and Exertional Collapse Associated With Sickle Cell Trait.具有挑战性的重返赛场决策:与镰状细胞性状相关的中暑、劳力性横纹肌溶解和劳力性虚脱。
Sports Health. 2016 Mar-Apr;8(2):117-25. doi: 10.1177/1941738115617453. Epub 2015 Nov 16.
2
Sickle Cell Trait from a Metabolic, Renal, and Vascular Perspective: Linking History, Knowledge, and Health.从代谢、肾脏和血管角度看镰状细胞特征:关联历史、知识和健康。
J Racial Ethn Health Disparities. 2015 Sep;2(3):330-5. doi: 10.1007/s40615-014-0077-4.
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Diagnostic evaluation of rhabdomyolysis.
横纹肌溶解症的诊断评估。
Muscle Nerve. 2015 Jun;51(6):793-810. doi: 10.1002/mus.24606. Epub 2015 Mar 14.
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Evaluation of creatine kinase activity and inorganic phosphate concentration in adult nigerian homozygous and heterozygous hemoglobin phenotypes.成年尼日利亚人纯合子和杂合子血红蛋白表型中肌酸激酶活性和无机磷酸盐浓度的评估。
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