He Z, Han S, Zhen Z, Ding X, Liang S
Department of Ophthalmology, Guangzhou Red Cross Hospital, China.
Yan Ke Xue Bao. 1990 Dec;6(3-4):111-2.
The present paper reports on the curative effect of the 0.1% Sodium hyaluronate (Na-HA) eyedrops jointly manufactured by Guangzhou Red Cross Hospital and Guangzhou Institute of Medical & Pharmaceutical Industry. 70 cases were studied. There were kerato-conjunctivitis sicca, lagophthalmos corneal fluorescein diffuse punctate epithelial lesion caused by contact lens, and keratitis punctata superficialis. The results showed effective treatment which occupied 95.7%. In the discussion, the authors point out that Na-HA has the same stagnatisity and elasticity as biotears because of its adhesion to the corneal epithelium. Moreover, it has the water-retaining microsponge action similar to that of mucopolysaccharide. Hence, Na-HA has protective effects on corneal epithelium. Finally, the authors conclude that Na-HA eyedrop is so far the most ideal substitute for tears and superior to other artificial tears.
本文报道了广州市红十字会医院与广州市医药工业研究所联合研制的0.1%透明质酸钠滴眼液的疗效。共研究了70例患者，包括干燥性角结膜炎、兔眼症、隐形眼镜所致角膜荧光素弥漫点状上皮病变以及浅层点状角膜炎。结果显示有效率达95.7%。在讨论中，作者指出透明质酸钠因其与角膜上皮的黏附性而具有与生物泪液相同的黏性和弹性，此外，它还具有与黏多糖类似的保水微海绵作用。因此，透明质酸钠对角膜上皮有保护作用。最后，作者得出结论，透明质酸钠滴眼液是迄今为止最理想的泪液替代品，优于其他人工泪液。
