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前交叉韧带断裂与骨关节炎进展

Anterior cruciate ligament rupture and osteoarthritis progression.

作者信息

Wong James Min-Leong, Khan Tanvir, Jayadev Chethan S, Khan Wasim, Johnstone David

机构信息

Chase Farm Hospital, The Ridgeway, Enfield, Middlesex, EN2 8JL, UK.

出版信息

Open Orthop J. 2012;6:295-300. doi: 10.2174/1874325001206010295. Epub 2012 Jul 27.

Abstract

Anterior Cruciate Ligament (ACL) rupture is a common sporting injury that frequently affects young, athletic patients. Apart from the functional problems of instability, patients with ACL deficient knees also develop osteoarthritis. Although this is frequently cited as an indication for ACL reconstruction, the relationship between ACL rupture, reconstruction and the instigation and progression of articular cartilage degenerative change is controversial.The purpose of this paper is to review the published literature with regards ACL rupture and the multifactorial causes for osteoarthritis progression, and whether or not this is slowed or stopped by ACL reconstruction.There is no evidence in the published literature to support the view that ACL reconstruction prevents osteoarthritis, although it may prevent further meniscal damage. It must be recognised that this conclusion is based on the current literature which has substantial methodological limitations.

摘要

前交叉韧带(ACL)断裂是一种常见的运动损伤,经常影响年轻的运动员患者。除了不稳定的功能问题外,ACL缺失膝关节的患者还会发展为骨关节炎。尽管这经常被认为是ACL重建的指征,但ACL断裂、重建与关节软骨退变改变的引发和进展之间的关系存在争议。本文的目的是回顾已发表的关于ACL断裂以及骨关节炎进展的多因素原因的文献,以及ACL重建是否能减缓或阻止这种进展。已发表的文献中没有证据支持ACL重建可预防骨关节炎的观点,尽管它可能预防进一步的半月板损伤。必须认识到,这一结论是基于目前存在大量方法学局限性的文献得出的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dd8/3415702/923c9b986e55/TOORTHJ-6-295_F1.jpg

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