Lang C
Neurologische Klinik, Univ. of Erlangen-Nürnberg.
Fortschr Med. 1990 Nov 20;108(33):625-9.
Alzheimer's disease is the most common form of dementia in the elderly. Owing to a lack of accurate easily determined clinical criteria, neuropathological findings remain decisive for establishing the diagnosis. However, full utilization of all the presently available methods, such as history taking, physical examination, neurological and mental status, psychological testing, laboratory examinations, additional procedures involving the use of diagnostic equipment, can result in a diagnostic accuracy of about 90%. The very wide spectrum of possible differential diagnostic possibilities can be greatly reduced by the judicious use of a few selective examinations. Here, the possibilities available in the doctor's office are better than ever before. Of decisive importance for the patient is to consider the possibility of dementia, and to exclude treatable causes as soon as possible.
阿尔茨海默病是老年人中最常见的痴呆形式。由于缺乏准确且易于确定的临床标准,神经病理学发现对于确诊仍然具有决定性意义。然而,充分利用目前所有可用的方法,如病史采集、体格检查、神经和精神状态评估、心理测试、实验室检查以及使用诊断设备的附加程序,诊断准确率可达约90%。通过明智地使用一些选择性检查,可以大大减少众多可能的鉴别诊断可能性。在此,医生办公室现有的检查手段比以往任何时候都更好。对患者来说,至关重要的是要考虑到痴呆的可能性,并尽快排除可治疗的病因。