Kesari Kavindra Kumar, Behari Jitendra
Bioelectromagnetic Laboratory, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, India.
Electromagn Biol Med. 2012 Sep;31(3):213-22. doi: 10.3109/15368378.2012.700292.
The relationship between radiofrequency electromagnetic fields emitted from mobile phone and infertility is a matter of continuing debate. It is postulated that these radiations may affect the reproduction pattern spell by targeting biochemistry of sperm. In an attempt to expedite the issue, 70 days old Wistar rats (n = 6) were exposed to mobile phone radiofrequency (RF) radiation for 2 h per day for 45 days and data compared with sham exposed (n = 6) group. A significant decrease (P < 0.05) in the level of testosterone and an increase in caspase-3 activity were found in the RF-exposed animals. Distortions in sperm head and mid piece of sperm mitochondrial sheath were also observed as captured by Transmission Electron Microscope (TEM). In addition, progeny from RF-exposed rats showed significant decreases in number and weight as compared with that of sham-exposed animals. A reduction in testosterone, an increase in caspase-3, and distortion in spermatozoa could be caused by overproduction of reactive oxygen species (ROS) in animals under mobile phone radiation exposure. Our findings on these biomarkers are clear indications of possible health implications of repeated exposure to mobile phone radiation.
手机发出的射频电磁场与不孕症之间的关系一直是个有争议的问题。据推测，这些辐射可能通过针对精子的生物化学过程来影响生殖模式。为了加快对这个问题的研究，将70日龄的Wistar大鼠（n = 6）每天暴露于手机射频（RF）辐射2小时，持续45天，并将数据与假暴露组（n = 6）进行比较。在暴露于射频的动物中，发现睾酮水平显著降低（P < 0.05），半胱天冬酶-3活性增加。通过透射电子显微镜（TEM）观察到精子头部和精子线粒体鞘中段也出现了扭曲。此外，与假暴露动物相比，暴露于射频的大鼠后代数量和体重显著减少。手机辐射暴露下的动物体内活性氧（ROS）过量产生可能导致睾酮减少、半胱天冬酶-3增加以及精子变形。我们对这些生物标志物的研究结果清楚地表明了反复暴露于手机辐射可能对健康产生的影响。
