对未接受药物治疗的波兰注意缺陷多动障碍男孩的生长情况评估。

Assessment of growth in pharmacological treatment-naïve Polish boys with attention-deficit/hyperactivity disorder.

作者信息

Hanć Tomasz, Cieślik Joachim, Wolańczyk Tomasz, Gajdzik Monika

机构信息

Department of Human Biological Development, Institute of Anthropology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.

出版信息

J Child Adolesc Psychopharmacol. 2012 Aug;22(4):300-6. doi: 10.1089/cap.2010.0113.

DOI:10.1089/cap.2010.0113

PMID:22897665

Abstract

OBJECTIVE

The objective of this study was to estimate the growth of pharmacological treatment-naïve polish boys with attention-deficit/hyperactivity disorder (ADHD).

METHOD

The sample included 135 boys (mean age: 11.67 years) with ADHD. The level of subjects' height, weight, and body mass index (BMI) was compared to the reference growth charts. Full estimation of measurement accuracy was provided. Regression analysis was used to estimate the biological and social factors contributing to the growth determination in the examined group.

RESULTS

There were no statistically significant differences between mean body height of boys with ADHD and standards of growth of Polish children. Separate analyses for body height of the examined boys aged 6-10, 11-15, and 16-18 years also gave no statistically significant results. Mean body weight (z=0.28) and BMI (z=0.25) in the total cohort were statistically higher than the norm. After categorization of the boys according to age, statistically significant differences were demonstrated only for weight in the age range of 6-10 years (z=0.31) and for BMI in the age range of 11-15y (z=0.42). The regression analysis showed the strongest relation between the subjects' growth and the parents' body size, newborn's condition (birth, body weight, and APGAR score), factors connected with lifestyle, and socio-economic status of the family.

CONCLUSION

The study revealed that the height of drug-naïve boys with ADHD was not significantly different from the norm. The investigation also showed a tendency for greater body weight and BMI in boys with ADHD in comparison with the growth charts, which may be manifested also in greater risk of overweight and obesity in this group. The results of research suggest the necessity to control for such variables as genetic, perinatal, socioeconomic, and psychosocial factors, which may affect children's development, in future research on the growth of children with ADHD.

摘要

目的

本研究的目的是评估未接受药物治疗的波兰患注意力缺陷多动障碍（ADHD）男孩的生长情况。

方法

样本包括135名患ADHD的男孩（平均年龄：11.67岁）。将受试者的身高、体重和体重指数（BMI）水平与参考生长图表进行比较。提供了测量准确性的全面评估。采用回归分析来估计影响受试组生长发育的生物学和社会因素。

结果

患ADHD男孩的平均身高与波兰儿童生长标准之间无统计学显著差异。对6 - 10岁、11 - 15岁和16 - 18岁受试男孩的身高进行单独分析，也未得出统计学显著结果。整个队列的平均体重（z = 0.28）和BMI（z = 0.25）在统计学上高于正常水平。根据年龄对男孩进行分类后，仅在6 - 10岁年龄组的体重（z = 0.31）和11 - 15岁年龄组的BMI（z = 0.42）方面显示出统计学显著差异。回归分析表明，受试者的生长与父母的体型、新生儿状况（出生情况、体重和阿氏评分）、与生活方式相关的因素以及家庭社会经济地位之间关系最为密切。

结论

该研究表明，未接受药物治疗的患ADHD男孩的身高与正常水平无显著差异。调查还显示，与生长图表相比，患ADHD男孩有体重和BMI更高的趋势，这可能也表现为该组超重和肥胖风险更高。研究结果表明，在未来关于患ADHD儿童生长发育的研究中，有必要控制可能影响儿童发育的遗传、围产期、社会经济和心理社会等变量。