Department of Psychiatry, Yale University, New Haven, Connecticut, USA.
Alcohol Clin Exp Res. 2012 Nov;36(11):1991-9. doi: 10.1111/j.1530-0277.2012.01812.x. Epub 2012 Aug 15.
Using alcohol at an early age is a well-documented risk factor for heavy drinking and the experience of a range of negative social and health consequences. However, it remains unclear if early consumption of any alcohol or early drinking to intoxication confers the greatest risk.
Age of onset (AO) and delay to first intoxication (delay) were examined as independent predictors of heavy drinking and the experience of alcohol-related problems (problems) in a sample of incoming college freshmen (n = 1,160) who completed biannual assessments from the summer following senior year of high school through senior year of college. The sample included more women (66%) than men and a majority were Caucasian (59%). We employed latent growth curve modeling to examine self-reported AO and delay to self-defined first intoxication as predictors of the frequency of heavy drinking and problems during year 4 of college, as well as changes in these alcohol-related outcomes from high school through college.
An earlier AO and/or a shorter delay was associated with increased frequency of heavy drinking and problems during senior year of college. Although individuals with a later AO and/or a longer delay were at lower risk overall, they showed larger increases in heavy drinking and problems over time.
The findings highlight the importance of distinguishing between AO and delay to first intoxication. Delay accounted for unique variance in drinking outcomes relative to AO, and the effects of AO were stronger when delay was included as a predictor variable. Results are discussed with regard to potential mechanisms through which an early age of intoxication may confer unique risk relative to AO. The implications for cross-cultural differences in risk for problems attributable to early drinking are also discussed.
早年饮酒是大量饮酒和经历一系列负面社会及健康后果的一个有充分记录的风险因素。然而,目前尚不清楚早期饮用任何酒精或早期饮酒至醉酒状态是否会带来最大的风险。
在一项对即将进入大学的新生(n=1160)进行的样本中,将发病年龄(AO)和首次醉酒的延迟时间(delay)作为独立预测因子,来评估重度饮酒和酒精相关问题(problems)的经历。该样本中女性(66%)多于男性,且大多数为白种人(59%)。我们采用潜在增长曲线模型,来检验自我报告的 AO 和自我定义的首次醉酒的延迟时间,作为大学四年级期间重度饮酒和问题发生频率的预测因子,以及这些与酒精相关的结果从高中到大学的变化。
较早的 AO 和/或较短的 delay 与大学高年级期间重度饮酒和问题发生的频率增加有关。虽然较晚的 AO 和/或较长的 delay 的个体总体上风险较低,但他们随着时间的推移在重度饮酒和问题方面的增长幅度更大。
研究结果强调了区分 AO 和首次醉酒延迟时间的重要性。与 AO 相比,延迟时间可以解释饮酒结果的差异,而当将 AO 作为预测变量时,AO 的影响更强。研究结果讨论了可能的机制,即醉酒年龄早可能会带来与 AO 不同的独特风险。还讨论了早期饮酒导致的问题归因于跨文化差异的风险的含义。