Morean Meghan E, Kong Grace, Camenga Deepa R, Cavallo Dana A, Connell Christian, Krishnan-Sarin Suchitra
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Alcohol Clin Exp Res. 2014 Oct;38(10):2615-21. doi: 10.1111/acer.12526. Epub 2014 Sep 24.
Quickly progressing from initiating alcohol use to drinking to intoxication recently was identified as a novel risk factor for hazardous drinking in college students (ME Morean et al. [2012] Alcohol Clin Exp Res, 36, 1991-1999). The current study evaluated the risk associated with age of onset (AO) and delay to first intoxication (Delay) in a high school sample.
Adolescent drinkers (N = 295, age 16.29 [1.14], 55.3% female, 80.3% Caucasian, AO = 13.51 [2.29] years, Delay = 0.80 [1.43] years) completed an anonymous survey about their substance use in February of 2010. Self-report questions assessed AO and age of first intoxication (AI) (i.e., "How old were you the first time you tried alcohol/got drunk?") and past-month alcohol use/binge drinking (i.e., How often did you drink alcohol/drink ≥5 drinks?).
Bivariate correlations indicated that AO was positively correlated with AI and inversely correlated with Delay, the frequency of any drinking, and the frequency of binge drinking. When considered alone, Delay was not significantly correlated with either alcohol use outcome. In contrast, hierarchical regression analyses indicated that when considered in concert, an earlier AO and a shorter Delay were each associated with heavier drinking (any drinking adjusted R(2) = 0.08; binge drinking R(2) = 0.06, p-values <0.001) beyond demographic characteristics. Two-way interactions among study variables were nonsignificant, suggesting that AO and Delay conferred risk similarly by racial/ethnic status, gender, and grade in high school.
When considered simultaneously, both an early AO and a quick progression to drinking to intoxication appear to be important determinants of high school student drinking. In addition to continuing efforts to postpone AO, efforts designed to delay intoxication may modulate alcohol-related risk associated with early drinking.
近期研究发现，从开始饮酒迅速发展到醉酒是大学生危险饮酒的一个新风险因素（ME·莫兰等人[2012年]《酒精临床与实验研究》，第36卷，第1991 - 1999页）。本研究评估了高中样本中与饮酒起始年龄（AO）和首次醉酒延迟时间（Delay）相关的风险。
2010年2月，青少年饮酒者（N = 295，年龄16.29岁[1.14]，55.3%为女性，80.3%为白种人，AO = 13.51岁[2.29]，Delay = 0.80年[1.43]）完成了一项关于其物质使用情况的匿名调查。自我报告问题评估了AO和首次醉酒年龄（AI）（即，“你第一次尝试饮酒/喝醉时多大？”）以及过去一个月的饮酒/暴饮情况（即，你多久饮酒一次/饮用≥5杯酒？）。
双变量相关性表明，AO与AI呈正相关，与Delay、任何饮酒频率和暴饮频率呈负相关。单独考虑时，Delay与任何饮酒结果均无显著相关性。相比之下，分层回归分析表明，当综合考虑时，较早的AO和较短的Delay均与更大量饮酒相关（任何饮酒调整后R² = 0.08；暴饮R² = 0.06，p值<0.001），超出人口统计学特征。研究变量之间的双向交互作用不显著，表明AO和Delay在种族/族裔身份、性别和高中年级方面赋予风险的方式类似。
同时考虑时，较早的AO和快速发展到醉酒似乎都是高中生饮酒的重要决定因素。除了继续努力推迟AO外，旨在延迟醉酒的努力可能会调节与早期饮酒相关的酒精风险。
