Niemcryk S J, Speers M A, Travis L B, Gary H E
Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston 77550.
J Psychosom Res. 1990;34(6):617-27. doi: 10.1016/0022-3999(90)90105-d.
To determine whether psychosocial variables are related to long-term glycemic control; trait anxiety, depression, loneliness and life stress were assessed in 48 Type I diabetic patients. Hemoglobin A1c (HbA1c), an indicator of long-term glycemic utilization, was assayed from blood samples drawn shortly before the self-report instruments were administered. Of the psychosocial variables, anxiety was significantly related to current values of HbA1c. The association between anxiety and current HbA1c remained after statistically controlling for potentially confounding variables, including the previous value of HbA1c. Despite the stability of HbA1c values over time, anxiety scores were not significantly correlated with follow-up HbA1c. The implications of the significant relationships between psychological constructs and glycemic control are discussed.
为了确定心理社会变量是否与长期血糖控制有关；对48名1型糖尿病患者进行了特质焦虑、抑郁、孤独感和生活压力评估。在自我报告工具施测前不久采集的血样中检测了糖化血红蛋白（HbA1c），它是长期血糖利用的一个指标。在心理社会变量中，焦虑与当前HbA1c值显著相关。在对包括先前HbA1c值在内的潜在混杂变量进行统计学控制后，焦虑与当前HbA1c之间的关联依然存在。尽管HbA1c值随时间保持稳定，但焦虑得分与随访时的HbA1c并无显著相关性。文中讨论了心理结构与血糖控制之间显著关系的意义。
