Department of Mechanical and Manufacturing Engineering, The University of Calgary, Calgary, Alberta, Canada.
Med Eng Phys. 2013 Apr;35(4):470-8. doi: 10.1016/j.medengphy.2012.06.012. Epub 2012 Aug 14.
To predict changes in the shape of the breast in different imaging devices, a Coupled Eulerian-Lagrangian (CEL) mechanical model is developed. The CEL method allows for a more adequate representation of the very large deformations experienced by the soft and incompressible tissues of the breast. The mechanical response of the tissues is based on advanced mathematical formulations and experimental data from the literature. Realistic geometries generated from Magnetic Resonance (MR) images are used as study cases. Furthermore, specific boundary conditions are applied to the model to predict the shape of the breast and the location of the internal tissues in a prototype microwave breast imaging system, where an immersion medium is used. The accuracy of the model was assessed by comparing the numerical results with a laser scan of the same subject in the microwave breast imaging system.
为了预测不同成像设备中乳房形状的变化，开发了一种耦合的欧拉-拉格朗日（CEL）力学模型。CEL 方法可以更充分地描述乳房的软组织和不可压缩组织经历的非常大的变形。组织的力学响应基于先进的数学公式和文献中的实验数据。使用从磁共振（MR）图像生成的真实几何形状作为研究案例。此外，模型应用了特定的边界条件来预测在原型微波乳房成像系统中的乳房形状和内部组织的位置，该系统中使用了浸入式介质。通过将数值结果与微波乳房成像系统中同一受试者的激光扫描进行比较，评估了模型的准确性。
