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[99mTc-SQ-30,217与201Tl心肌闪烁显像在心肌梗死病例中的对比研究]

[A comparative study of myocardial scintigraphy with 99mTc-SQ-30,217 and 201Tl in cases with myocardial infarction].

作者信息

Kawakami K, Iwamura A, Goto E, Mori Y, Aoki M, Miyazawa S, Shibata T, Shimada T

机构信息

Department of Radiology, Jikei University School of Medicine.

出版信息

Kaku Igaku. 1990 Dec;27(12):1447-50.

PMID:2290217
Abstract

A comparative study of myocardial scintigraphy with 99mTc-SQ-30217 (SQ) and 201Tl was performed in 6 patients having ischemic heart diseases which were confirmed by the coronary angiography. The SQ study was done 1 week after the 201Tl study. Both studies were performed in exercise and resting state. Degree of perfusion defect was compared between SQ and 201Tl SPECT by means of scoring 0-2 (0: no defect, 1: equivocal, 2: definite defect) by five doctors (two physicians and three radiologists). Ability of this agent to detect the ischemic lesions was similar to that of 201Tl except for two regions. Effect of the liver image on the evaluation of the inferior wall of the left ventricle was small on this study, although the hepatic accumulation of the tracer was prominent. This agent is a promising tracer for the evaluation of myocardial perfusion in the cases with myocardial infarction.

摘要

对6例经冠状动脉造影确诊为缺血性心脏病的患者进行了99mTc-SQ-30217(SQ)与201Tl心肌闪烁显像的对比研究。SQ研究在201Tl研究1周后进行。两项研究均在运动和静息状态下进行。由五位医生(两名内科医生和三名放射科医生)通过0-2分评分(0:无缺损,1:可疑,2:明确缺损)比较了SQ和201Tl单光子发射计算机断层扫描(SPECT)的灌注缺损程度。除两个区域外,该药物检测缺血性病变的能力与201Tl相似。尽管示踪剂在肝脏的蓄积明显,但在本研究中肝脏影像对左心室下壁评估的影响较小。该药物是用于评估心肌梗死患者心肌灌注的一种有前景的示踪剂。

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