Flaum Eye Institute, University of Rochester, Rochester, NY 14624, USA.
J Cataract Refract Surg. 2012 Oct;38(10):1724-33. doi: 10.1016/j.jcrs.2012.05.032. Epub 2012 Aug 15.
To measure the impact of corneal aberrations on the through-focus image quality of presbyopia-correcting intraocular lenses (IOLs) using an adaptive optics IOL metrology system.
Flaum Eye Institute, University of Rochester, Rochester, New York, USA.
Experimental study.
An adaptive optics IOL metrology system comprising a model eye, wavefront sensor, deformable mirror, and an image-capturing device acquired through-focus images of a letter chart with 3.0 mm and 5.0 mm pupil diameters. The system was used to induce corneal astigmatism and higher-order aberrations (HOAs) in previously measured pseudophakic presbyopic eyes. A single-optic accommodating IOL (Crystalens HD (HD500), an apodized (Restor +3.0 diopter [D] SN6AD1) and full-aperture (Tecnis ZM900) diffractive multifocal IOL, and a monofocal IOL (Acrysof SN60AT) were evaluated. Image quality was quantified using the correlation-coefficient image-quality metric.
The single-optic accommodating IOL and monofocal IOL performed similarly; however, with a 3.0 mm pupil, the former had better intermediate (1.50 D) image quality. The multifocal IOLs had bimodal through-focus image quality trends. Corneal astigmatism reduced through-focus image quality and depth of focus with all IOLs; however, the multifocal IOLs had the most severe decline in depth of focus. Ocular spherical aberration had the strongest impact on image quality when typical pseudophakic corneal HOAs were present.
The uncorrected corneal astigmatism and HOAs in pseudophakic eyes significantly affected through-focus performance of presbyopia-correcting IOLs. Although multifocal IOLs significantly increased depth of focus, this benefit diminished when more than 0.75 D astigmatism remained uncorrected. Residual ocular spherical aberration had a significant effect on image quality in the presence of other corneal HOAs.
使用自适应光学人工晶状体（IOL）测量系统测量角膜像差对老视矫正 IOL 的远近距离焦点图像质量的影响。
美国罗切斯特大学弗莱姆眼科研究所。
实验研究。
自适应光学 IOL 测量系统包括模型眼、波前传感器、变形镜和图像采集设备，通过 3.0mm 和 5.0mm 瞳孔直径的字母图表获取远近距离焦点图像。该系统用于在先前测量的非白内障性老视眼中诱发角膜散光和高阶像差（HOA）。评估了一种单光调节 IOL（Crystalens HD（HD500））、一种非球面前加光（Restor +3.0 屈光度 [D] SN6AD1）和全孔径（Tecnis ZM900）衍射多焦点 IOL 以及一种单焦点 IOL（Acrysof SN60AT）。使用相关系数图像质量度量来量化图像质量。
单光调节 IOL 和单焦点 IOL 的性能相似；然而，在 3.0mm 瞳孔时，前者具有更好的中间（1.50D）图像质量。多焦点 IOL 具有双峰远近距离焦点图像质量趋势。所有 IOL 都降低了角膜散光的远近距离焦点图像质量和景深；然而，多焦点 IOL 的景深下降最为严重。在存在典型的人工晶状体后角膜 HOA 时，眼的球差对图像质量的影响最大。
人工晶状体后未矫正的角膜散光和 HOA 显著影响老视矫正 IOL 的远近距离焦点性能。尽管多焦点 IOL 显著增加了景深，但当未矫正的散光超过 0.75D 时，这种益处会减弱。在存在其他角膜 HOA 的情况下，残余眼的球差对图像质量有显著影响。
