Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Science. 2012 Sep 28;337(6102):1628. doi: 10.1126/science.1226355. Epub 2012 Aug 16.
Digital information is accumulating at an astounding rate, straining our ability to store and archive it. DNA is among the most dense and stable information media known. The development of new technologies in both DNA synthesis and sequencing make DNA an increasingly feasible digital storage medium. We developed a strategy to encode arbitrary digital information in DNA, wrote a 5.27-megabit book using DNA microchips, and read the book by using next-generation DNA sequencing.
数字信息正以惊人的速度积累，这使得我们存储和归档信息的能力面临挑战。DNA 是已知最密集和最稳定的信息载体之一。DNA 合成和测序技术的新发展使得 DNA 成为一种越来越可行的数字存储介质。我们开发了一种在 DNA 中编码任意数字信息的策略，使用 DNA 微芯片编写了一本 527 万比特的书，并通过使用下一代 DNA 测序技术来读取这本书。
