State Key Laboratory and Institute of Elemento-organic Chemistry Nankai University, Tianjin 300071, People's Republic of China.
Org Biomol Chem. 2012 Oct 7;10(37):7628-34. doi: 10.1039/c2ob26338f. Epub 2012 Aug 17.
A novel phosphine-catalyzed intermolecular [3 + 2] cycloaddition of ynones and N-substituted isatins was developed. In this reaction, substituted ynones, serving as a C(3) synthon, were successfully applied in intermolecular annulation reactions. A number of functionalized spirooxazolines were obtained in high yields and stereoselectivity.
发展了一种新型膦催化的炔酮与 N-取代靛红的分子间[3+2]环加成反应。在该反应中，取代的炔酮作为 C(3)合成子，成功地应用于分子间环化反应中。得到了一系列功能化的螺噁唑啉，具有较高的产率和立体选择性。
