Department and Research Center of Otolaryngology, Head and Neck Surgery, Hazrat Rasoul Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Eur Arch Otorhinolaryngol. 2013 Mar;270(3):1131-6. doi: 10.1007/s00405-012-2157-6. Epub 2012 Aug 19.
Obstructive sleep apnea (OSA) is a common sleep disorder affecting quality of life. The aim of this study was to evaluate the perception of Quality of Life (QOL) in patients with OSA by means of World Health Organization Quality of Life (WHOQOL-BREF) instrument. This study was conducted on adult patients with sleep problems referred to Noor Sleep Lab for an overnight sleep study. Subjects were assessed for QOL using WHOQOL-BREF questionnaire. The Epworth sleepiness scale (ESS) was also employed to assess excessive daytime sleepiness (EDS). Baseline characteristics, ESS, and measured QOL are reported and their correlations with QOL were examined. Out of 502 patients included in the study, 62.7 % had moderate to severe OSA. The mean score of QOL in physical domain was significantly lower compared with normative population data. While AHI did not show any correlation with quality of life, mean O(2) was weakly correlated with physical domain. Among the baseline characteristics, BMI and ESS were negatively correlated with physical and mental domains. Findings of this study show the impairment in quality of life related to physical functioning in patients with obstructive sleep apnea. Our study further supports the lack of association between AHI and QOL.
阻塞性睡眠呼吸暂停（OSA）是一种常见的影响生活质量的睡眠障碍。本研究旨在通过世界卫生组织生活质量（WHOQOL-BREF）量表评估 OSA 患者的生活质量感知。这项研究是在因睡眠问题而被转介到 Noor 睡眠实验室进行整夜睡眠研究的成年患者中进行的。使用 WHOQOL-BREF 问卷评估患者的生活质量。还使用 Epworth 嗜睡量表（ESS）评估白天过度嗜睡（EDS）。报告了基线特征、ESS 和测量的生活质量，并检查了它们与生活质量的相关性。在纳入研究的 502 名患者中，62.7%的患者患有中重度 OSA。与规范人群数据相比，身体领域的生活质量平均得分明显较低。虽然 AHI 与生活质量没有相关性，但平均 O(2)与身体领域呈弱相关性。在基线特征中，BMI 和 ESS 与身体和心理领域呈负相关。这项研究的结果表明，阻塞性睡眠呼吸暂停患者的身体功能受损与生活质量下降有关。我们的研究进一步支持 AHI 与生活质量之间缺乏关联。
