Demir B, Arikan I I, Bozdag G, Esinler I, Karakoc Sokmensuer L, Gunalp S
Department of Gynecology and Obstetrics, Ergani State Hospital, Diyarbakir, Turkey.
Clin Exp Obstet Gynecol. 2012;39(2):144-6.
To assess the effect of isolated teratozoospermia with a normal sperm count and total motility by means of the fertilization rates, embryo quality and clinical pregnancy rate only in ICSI cycles.
We retrospectively analyzed the records of patients who underwent ICSI at Hacettepe University, Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Fertility and Reproductive Endocrinology between July 2001 and January 2010. Only patients with normal sperm count and total motility were recruited. The remaining cycles were further divided into two groups according to their sperm morphology with respect to Kruger's strict criteria. In Group 1, 537 consecutive cycles were enrolled whose sperm morphology was <4%. In Group 2, 118 cycles were identified with a morphology of > or = 4%.
A total of 655 ICSI cycles were included in the final analysis. The fertilization rates were 72.0% and 70.8% in Groups 1 and 2, respectively. There were no differences regarding embryo quality, clinical pregnancy and implantation rates between the two groups.
Our data suggest that detection of morphology defect has no value in the prediction of fertilization, embryo quality and clinical pregnancy in ICSI cycles.
仅在卵胞浆内单精子注射（ICSI）周期中，通过受精率、胚胎质量和临床妊娠率来评估精子计数和总活力正常的孤立性畸形精子症的影响。
我们回顾性分析了2001年7月至2010年1月在哈杰泰佩大学医学院妇产科生育与生殖内分泌科接受ICSI治疗的患者记录。仅招募精子计数和总活力正常的患者。其余周期根据精子形态按照克鲁格严格标准进一步分为两组。在第1组中，纳入了537个连续周期，其精子形态<4%。在第2组中，确定了118个周期，其形态≥4%。
最终分析共纳入655个ICSI周期。第1组和第2组的受精率分别为72.0%和70.8%。两组之间在胚胎质量、临床妊娠和着床率方面没有差异。
我们的数据表明，在ICSI周期中，形态缺陷的检测对受精、胚胎质量和临床妊娠的预测没有价值。
