Cancer Biology Proteomic Groups, University of Hull, HYMS, Hull, UK.
World J Surg Oncol. 2012 Aug 20;10:166. doi: 10.1186/1477-7819-10-166.
Xanthogranulomatous inflammation is a rare clinico-pathological condition involving many organ systems. Breast involvement with this rare condition reported from a few cases of mastitis has been limited to only microscopic involvement on histology. We would like to report an unusual presentation of this inflammatory process presenting as a solid lump mimicking malignancy in latissimus dorsi donor site scar and implant-based breast reconstruction as a result of a ruptured silicone gel implant. To our knowledge there have been no previous reports on similar presentation published in the literature. This case highlights a rare complication of a leaked silicone gel implant triggering a xanthomatous response in the absence of the usual infective or obstructing etiologies. This condition is of benign nature with complete clearance on surgical excision and excellent clinical prognosis reported from other organ involvement.
黄色肉芽肿性炎症是一种罕见的临床病理情况,涉及许多器官系统。乳腺受累的这种罕见情况仅在少数乳腺炎病例的组织学中表现为显微镜下受累。我们报告了一例不寻常的炎症过程,表现为胸腰背部供区瘢痕和基于植入物的乳房重建的实性肿块,类似于恶性肿瘤,这是由于硅凝胶植入物破裂所致。据我们所知,文献中尚无类似表现的报道。本病例强调了漏硅凝胶植入物引发黄色瘤反应的罕见并发症,而无常见的感染或阻塞病因。这种情况是良性的,通过手术切除可完全清除,其他器官受累的临床预后良好。