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使用聚乙醇酸:碳酸三亚甲基酯补片修复食管裂孔疝的初步研究。

Preliminary study of hiatal hernia repair using polyglycolic acid: trimethylene carbonate mesh.

作者信息

Massullo James M, Singh Tejinder P, Dunnican Ward J, Binetti Brian R

机构信息

Department of General Surgery, Albany Medical Center, Albany, NY, USA.

出版信息

JSLS. 2012 Jan-Mar;16(1):55-9. doi: 10.4293/108680812X13291597715943.

Abstract

BACKGROUND

Repairing large hiatal hernias using mesh has been shown to reduce recurrence. Drawbacks to mesh include added time to place and secure the prosthesis as well as complications such as esophageal erosion. We used a laparoscopic technique for repair of hiatal hernias (HH) >5cm, incorporating primary crural repair with onlay fixation of a synthetic polyglycolicacid:trimethylene carbonate (PGA:TMC) absorbable tissue reinforcement. The purpose of this report is to present short-term follow-up data.

METHODS

Patients with hiatal hernia types I-III and defects >5cm were included. Primary closure of the hernia defect was performed using interrupted nonpledgeted sutures, followed by PGA:TMC mesh onlay fixed with absorbable tacks. A fundoplication was then performed. Evaluation of patients was carried out at routine follow-up visits. Outcomes measured were symptoms of gastroesophageal reflux disease (GERD), or other symptoms suspicious for recurrence. Patients exhibiting these complaints underwent further evaluation including radiographic imaging and endoscopy.

RESULTS

Follow-up data were analyzed on 11 patients. Two patients were male; 9 were female. The mean age was 60 years. The mean length of follow-up was 13 months. There were no complications related to the mesh. One patient suffered from respiratory failure, one from gas bloat syndrome, and another had a superficial port-site infection. One patient developed a recurrent hiatal hernia.

CONCLUSIONS

In this small series, laparoscopic repair of hiatal hernias >5cm with onlay fixation of PGA:TMC tissue reinforcement has short-term outcomes with a reasonably low recurrence rate. However, due to the preliminary and nonrandomized nature of the data, no strong comparison can be made with other types of mesh repairs. Additional data collection is warranted.

摘要

背景

使用补片修复大型食管裂孔疝已被证明可降低复发率。补片的缺点包括放置和固定假体所需的额外时间以及诸如食管侵蚀等并发症。我们采用腹腔镜技术修复直径>5cm的食管裂孔疝(HH),采用原发性膈肌脚修复并覆盖固定合成聚乙醇酸:碳酸三亚甲基酯(PGA:TMC)可吸收组织增强材料。本报告的目的是呈现短期随访数据。

方法

纳入患有I-III型食管裂孔疝且缺损>5cm的患者。使用间断无垫片缝线对疝缺损进行一期缝合,随后用可吸收钉将PGA:TMC补片覆盖固定。然后进行胃底折叠术。在常规随访时对患者进行评估。测量的结果为胃食管反流病(GERD)症状或其他可疑复发症状。出现这些症状的患者接受进一步评估,包括影像学检查和内镜检查。

结果

对11例患者的随访数据进行了分析。2例为男性,9例为女性。平均年龄为60岁。平均随访时间为13个月。没有与补片相关的并发症。1例患者发生呼吸衰竭,1例发生气胀综合征,另1例发生浅表切口感染。1例患者出现复发性食管裂孔疝。

结论

在这个小系列研究中,采用PGA:TMC组织增强材料覆盖固定的腹腔镜修复直径>5cm的食管裂孔疝具有短期疗效,复发率相对较低。然而,由于数据的初步性和非随机性,无法与其他类型的补片修复进行有力比较。需要收集更多数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/3407458/54f324e543fb/jls0011228270001.jpg

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