Zmora O, Stolik-Dollberg O, Bar-Zakai B, Rosin D, Kuriansky J, Shabtai M, Perel A, Ayalon A
Department of Surgery, Chaim Sheba Medical Center, Sackler School of Medicine, Tel Aviv, Israel.
JSLS. 2000 Oct-Dec;4(4):301-4.
Laparoscopic cholecystectomy is characterized by a short hospital stay. Hence, pain control on the day of surgery is increasingly important. The aim of this study was to evaluate the effect of intraperitoneal bupivacaine on pain relief following laparoscopic cholecystectomy.
Sixty patients undergoing elective laparoscopic cholecystectomy were prospectively randomized into 2 groups. Following removal of the gallbladder, group A received 100 mg of bupivacaine in 50 cc of saline, installed into the gallbladder bed and right subphrenic space. Group B received saline without bupivacaine. Pain was assessed using a visual/analog scale at fixed-time intervals.
No significant difference occurred in the average pain levels between the groups at 1, 2, 4, and 14 hours postsurgery. The average analgesic requirement was lower in the bupivacaine group, but this did not reach statistical significance.
Application of intraperitoneal bupivacaine did not attenuate pain following laparoscopic cholecystectomy, and no role exists for its routine use.
腹腔镜胆囊切除术的特点是住院时间短。因此，手术当天的疼痛控制变得越来越重要。本研究的目的是评估腹腔内注射布比卡因对腹腔镜胆囊切除术后疼痛缓解的效果。
60例行择期腹腔镜胆囊切除术的患者被前瞻性随机分为2组。切除胆囊后，A组在50毫升生理盐水中加入100毫克布比卡因，注入胆囊床和右膈下间隙。B组接受不含布比卡因的生理盐水。使用视觉模拟量表在固定时间间隔评估疼痛。
术后1、2、4和14小时，两组的平均疼痛水平无显著差异。布比卡因组的平均镇痛需求较低，但未达到统计学意义。
腹腔内注射布比卡因并不能减轻腹腔镜胆囊切除术后的疼痛，其常规使用没有作用。
